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GW182 Antibody [DyLight 650]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, KD
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

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GW182 Antibody [DyLight 650] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 575 and 625 of human GW182/glycine-tryptophan protein of 182 kDa (NP_055309.2).
Marker
P/GW Body Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNRC6A
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoblotting
  • Knockdown Validated
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in (PMID: 29935344).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GW182 Antibody [DyLight 650]

  • CAG repeat protein 26
  • CAGH26FLJ22043
  • DKFZp666E117
  • EMSY interactor protein
  • Glycine-tryptophan protein of 182 kDa
  • GW182 autoantigen
  • GW182GW1
  • KIAA1460EDIE
  • MGC75384
  • Protein GW1
  • TNRC6
  • trinucleotide repeat containing 6
  • trinucleotide repeat containing 6A
  • trinucleotide repeat-containing gene 6A protein

Background

GW182 (glycine-tryptophan protein of 182 kDa) is a member of the trinucleotide repeat containing 6 protein family. It functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. GW182 has been found to associate with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibition of GW182 expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TNRC6A