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Gremlin 1 Antibody (C1)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

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Gremlin 1 Antibody (C1) Summary

Immunogen
Immunized with recombinant Human Gremlin 1 (Uniprot#: O60565; Lys26-Asp184 (Uniprot#: O60565)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GREM1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-30ug/mL
  • Western Blot 0.5-3ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Gremlin 1 Antibody (C1)

  • Cell proliferation-inducing gene 2 protein
  • CKTSF1B1gremlin 1, cysteine knot superfamily, homolog
  • Cysteine knot superfamily 1, BMP antagonist 1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)
  • DAN domain family member 2
  • DAND2
  • DAND2GREMLIN
  • Down-regulated in Mos-transformed cells protein
  • DRM
  • DRMMGC126660
  • GREM1
  • gremlin 1
  • gremlin 1-like protein
  • Gremlin
  • gremlin-1
  • IHG-2
  • Increased in high glucose protein 2
  • increased in high glucose-2
  • proliferation-inducing gene 2

Background

In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gremlin 1 Antibody
(C1)
NBP3-41762
Gremlin 1 Antibody (C1)
Species: Hu
Applications: WB, IHC

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Bioinformatics

Gene Symbol GREM1