GluR2 Antibody Summary
Immunogen |
Synthetic peptide corresponding to amino acid residues specific to GluR2 conjugated to KLH. Accession # P19491 |
Localization |
Cell Membrane |
Specificity |
Specific for endogenous levels of the ~100 kDa GluR2 protein. |
Predicted Species |
Human (100%), Mouse (100%), Zebrafish (100%), Chicken (100%), Primate (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
GRIA2 |
Purity |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
|
Theoretical MW |
100 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Control |
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Reactivity Notes
Tested in Rat. It is anticipated that the antibody will also react with chicken, human, mouse, non-human primates and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol |
Preservative |
No Preservative |
Purity |
Antigen Affinity-purified |
Alternate Names for GluR2 Antibody
Background
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D- aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by -amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Control Lysate(s)
Secondary Antibodies
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