GIT1 Antibody (S39B-8)

G-protein-coupled receptor kinase interactor 1 (GIT1) and G-protein-coupled receptor kinase interactor 2 (GIT2) are GTPase-activating proteins for ADP-ribosylation (Arf) GTPases. GIT1 and GIT2 regulate Arf activity and the sequestration of activated G protein-coupled receptors from the surface of the cell. These activities have effects on multiple cellular processes such as cell migration, T-cell activation, and centrosome dynamics. Both GIT proteins also serve as scaffolds to link signaling molecules. Alternative names for GIT1 include GRK-interacting protein 1, cool-associated and tyrosine phosphorylated protein 1, and Cat-1.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 7 applications: ICC/IF, IHC-F, IHC-Fr, IP, KO, PLA, WB.

Showing Publications 1 - 7 of 7.

Publications using NBP2-22423	Applications	Species
Schlienger, S;Yam, PT;Balekoglu, N;Ducuing, H;Michaud, JF;Makihara, S;Kramer, DK;Chen, B;Fasano, A;Berardelli, A;Hamdan, FF;Rouleau, GA;Srour, M;Charron, F; Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control Science advances 2023-05-12 [PMID: 37172092] (IHC-Fr, PLA, ICC/IF, WB, Mouse)	IHC-Fr, PLA, ICC/IF, WB	Mouse
Wan B, Li C, Wang M et al. GIT1 protects traumatically injured spinal cord by prompting microvascular endothelial cells to clear myelin debris Aging (Albany NY) 2021-03-15 [PMID: 33621952]
Zhao SJ, Liu H, Chen J et al. Macrophage GIT1 contributes to bone regeneration by regulating inflammatory responses in an ERK/NRF2-dependent way J. Bone Miner. Res. 2020-05-27 [PMID: 32460388] (WB, KO, Mouse)	WB, KO	Mouse
Huang Y, Gu C, Wang Q, et al. The protective effort of GPCR kinase 2 interacting protein 1 in neurons via promoting Beclin1 Parkin induced mitophagy at the early stage of spinal cord ischemia reperfusion injury FASEB j. 2019-12-27 [PMID: 31908016] (ICC/IF, WB, IHC-F, Mouse)	ICC/IF, WB, IHC-F	Mouse
Li L, Tang P, Zhou Z et al. GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF-kappa B/Notch signalling to promote angiogenesis Cell Prolif. [PMID: 31502302] (IP)	IP
Zhao SJ, Kong FQ, Cai W et al. GIT1 contributes to autophagy in osteoclast through disruption of the binding of Beclin1 and Bcl2 under starvation condition Cell Death Dis 2018-12-13 [PMID: 30546041] (WB, Mouse)	WB	Mouse
Chen J, Wang Q, Zhou W et al. GPCR kinase 2-interacting protein-1 protects against ischemia-reperfusion injury of the spinal cord by modulating ASK1/JNK/p38 signaling FASEB J. [PMID: 29912587]

Array NBP2-22423

• GIT1 Antibodies
• GIT1 Lysate
• GIT1 Proteins
• GIT1 ELISA