EMMPRIN/CD147 Antibody Pair [HRP] Summary
Description |
Solid Phase sandwich ELISA for the quantitative determination of Human EMMPRIN/CD147. |
Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human EMMPRIN/CD147. |
Standard Curve Range |
6.25-400 pg/ml (example only; lot dependent) |
Sensitivity |
6.25 pg/ml (example only; lot dependent) |
Assay Type |
Sandwich ELISA |
Sample Volume |
100 ul |
Gene |
BSG |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Mouse Monoclonal Capture Antibody
- Standard
|
Alternate Names for EMMPRIN/CD147 Antibody Pair [HRP]
Background
CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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