Reactivity | HuSpecies Glossary |
Applications | Func, PAGE |
Concentration | 1 mg/ml |
Description | A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-441 of Human EED Source: E.coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEREVS TAPAGTDMPA AKKQKLSSDE NSNPDLSGDE NDDAVSIESG TNTERPDTPT NTPNAPGRKS WGKGKWKSKK CKYSFKCVNS LKEDHNQPLF GVQFNWHSKE GDPLVFATVG SNRVTLYECH SQGEIRLLQS YVDADADENF YTCAWTYDSN TSHPLLAVAG SRGIIRIINP ITMQCIKHYV GHGNAINELK FHPRDPNLLL SVSKDHALRL WNIQTDTLVA IFGGVEGHRD EVLSADYDLL GEKIMSCGMD HSLKLWRINS KRMMNAIKES YDYNPNKTNR PFISQKIHFP DFSTRDIHRN YVDCVRWLGD LILSKSCENA IVCWKPGKME DDIDKIKPSE SNVTILGRFD YSQCDIWYMR FSMDFWQKML ALGNQVGKLY VWDLEVEDPH KAKCTTLTHH KCGAAIRQTS FSRDSSILIA VCDDASIWRW DRLR |
Source | E. coli |
Protein/Peptide Type | Recombinant Protein |
Gene | EED |
Purity | >90%, by SDS-PAGE |
Dilutions |
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Application Notes | Use in In vitro reported in scientific literature (PMID:34093859) |
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Theoretical MW | 52.6 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer | 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 10% glycerol, 1 mM DTT |
Preservative | No Preservative |
Concentration | 1 mg/ml |
Purity | >90%, by SDS-PAGE |
Publication using NBP2-23020 | Applications | Species |
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Li X, Gera L, Zhang S et al. Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer Theranostics 2021-05-08 [PMID: 34093859] (In vitro) | In vitro |
Research Areas for EED Recombinant Protein (NBP2-23020)Find related products by research area.
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Microglia: pruning shears for homeostatic maintenance in the brain By Jennifer Sokolowski, MD, PhD.Microglia play a critical role in pruning neurons and synapses during homeostatic maintenance in the adult brain.1 A recent study by Ayata et al. (2018) identified regional differe... Read full blog post. |
EZH1 has more to offer than gene repression EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development. Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2. PR... Read full blog post. |
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Gene Symbol | EED |