DOCK1 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: DOCK1 Antibody [NBP2-58639] - Staining of human cell line A549 shows localization to nuclear speckles.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

DOCK1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: VRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKE
Predicted Species
Mouse (94%), Rat (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DOCK1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
DOCK1 Recombinant Protein Antigen (NBP2-58639PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for DOCK1 Antibody

  • 180 kDa protein downstream of CRK
  • ced5
  • dedicator of cytokinesis 1
  • dedicator of cyto-kinesis 1
  • DOCK1
  • DOCK180
  • DOCK180dedicator of cytokinesis protein 1
  • DOwnstream of CrK

Background

DOCK80 is a non-conventional Rho-guanine nucleotide exchange factor (Rho-GEF) that functions to activate the small GTPases Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2. Dock180 functions to activate Rac and regulate cell adhesion, cell spreading, migration and phagocytosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for DOCK1 Antibody (NBP2-58639) (0)

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Secondary Antibodies

 

Isotype Controls

Additional DOCK1 Products

Array NBP2-58639

Research Areas for DOCK1 Antibody (NBP2-58639)

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Contact Information

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Bioinformatics

Gene Symbol DOCK1