Species: Hu, Mu, Rt, Ze
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ca
Applications: WB
Host: Goat Polyclonal
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
DOCK80 is a non-conventional Rho-guanine nucleotide exchange factor (Rho-GEF) that functions to activate the small GTPases Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2. Dock180 functions to activate Rac and regulate cell adhesion, cell spreading, migration and phagocytosis.
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
1793 |
| Alternate Names |
- 180 kDa protein downstream of CRK
- ced5
- dedicator of cytokinesis 1
- dedicator of cyto-kinesis 1
- DOCK180dedicator of cytokinesis protein 1
- DOwnstream of CrK
|
Research Areas for DOCK1
Find related products by research area and learn more about each of the different research areas below.
Apoptosis
