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DEPTOR/DEPDC6 Antibody [HRP]

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Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, ICC/IF, IHC, KO
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

Order Details

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DEPTOR/DEPDC6 Antibody [HRP] Summary

Immunogen
A genomic peptide made to an internal region of the human DEPTOR protein (within residues 10-200). [Swiss-Prot: Q8TB45]
Localization
Intracellular.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DEPTOR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 31176743).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for DEPTOR/DEPDC6 Antibody [HRP]

  • DEP domain containing 6
  • DEP domain containing mTOR interacting protein
  • DEP domain containing MTOR-interacting protein
  • DEP domain-containing mTOR-interacting protein
  • DEP domain-containing protein 6
  • DEP.6
  • DEPDC6
  • DEPDC6FLJ12341
  • DEPTOR
  • DKFZp564B1778
  • FLJ12428
  • FLJ13854

Background

Deptor interacts with the mammalian target of rapamycin (mTOR), inhibiting kinase activities and ultimately negatively regulating the downstream mTOR pathways. Because of its critical role in signaling, changes in expression levels of Deptor can lead to hyperplasia, apoptosis, and several cancers. Deptor seems to lead to cytokine cascades that are important in endometriosis and the induction of labor. Through mTOR interactions, Deptor is implicated in pathways for cell growth and differentiation, as well as cell-cycle prolongation or termination.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DEPTOR/DEPDC6 Antibody (NBP1-49674H) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DEPTOR