DEPTOR/DEPDC6 Antibody [HRP] Summary
Immunogen |
A genomic peptide made to an internal region of the human DEPTOR protein (within residues 10-200). [Swiss-Prot: Q8TB45] |
Localization |
Intracellular. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
DEPTOR |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Knockout Validated
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Readout System |
|
Reactivity Notes
Rat reactivity reported in scientific literature (PMID: 31176743).
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
No Preservative |
Purity |
Immunogen affinity purified |
Alternate Names for DEPTOR/DEPDC6 Antibody [HRP]
Background
Deptor interacts with the mammalian target of rapamycin (mTOR), inhibiting kinase activities and ultimately negatively regulating the downstream mTOR pathways. Because of its critical role in signaling, changes in expression levels of Deptor can lead to hyperplasia, apoptosis, and several cancers. Deptor seems to lead to cytokine cascades that are important in endometriosis and the induction of labor. Through mTOR interactions, Deptor is implicated in pathways for cell growth and differentiation, as well as cell-cycle prolongation or termination.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for DEPTOR/DEPDC6 Antibody (NBP1-49674H) (0)
Secondary Antibodies
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Isotype Controls
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