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Glycine N-Methyltransferase/GNMT Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: Glycine N-Methyltransferase/GNMT Antibody [NBP1-89512] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
Orthogonal Strategies: Immunohistochemistry-Paraffin: Glycine N-Methyltransferase/GNMT Antibody [NBP1-89512] - Staining in human pancreas and colon tissues using anti-GNMT antibody. Corresponding GNMT RNA-seq ...read more
Immunohistochemistry-Paraffin: Glycine N-Methyltransferase/GNMT Antibody [NBP1-89512] - Staining of human colon shows low expression as expected.
Immunohistochemistry-Paraffin: Glycine N-Methyltransferase/GNMT Antibody [NBP1-89512] - Staining of human pancreas shows high expression.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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Glycine N-Methyltransferase/GNMT Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY
Predicted Species
Rat (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GNMT
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Glycine N-Methyltransferase/GNMT Protein (NBP1-89512PEP)
Publications
Read Publication using NBP1-89512.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Glycine N-Methyltransferase/GNMT Antibody

  • EC 2.1.1.20
  • Glycine NMethyltransferase
  • Glycine N-Methyltransferase
  • GNMT

Background

GNMT is encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Glycine N-Methyltransferase/GNMT Antibody (NBP1-89512)(1)

Reviews for Glycine N-Methyltransferase/GNMT Antibody (NBP1-89512) (0)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Glycine N-Methyltransferase/GNMT Antibody (NBP1-89512) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GNMT