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DAP Kinase 1 [p Ser308] Antibody (DKPS308) - BSA Free

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Western Blot: DAP Kinase 1 [p Ser308] Antibody (DKPS308) [NB120-10524] - Whole extract of HEK-293 cells overexpressing human DAP Kinase was separated on SDS-PAGE and probed with 1 ug/mL Monoclonal ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP, MA
Clone
DKPS308
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
2.0 mg/ml

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DAP Kinase 1 [p Ser308] Antibody (DKPS308) - BSA Free Summary

Immunogen
Synthetic peptide, corresponding to amino acids 303-312 (pSer308) of Human DAP Kinase 1.
Modification
p Ser308
Localization
Cytoplasmic
Specificity
DAP Kinase 1 Phosphospecific (DKPS308) [Ser308]
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
DAPK1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Microarray
  • Western Blot 1 - 2 ug/mL
Theoretical MW
160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
DAP Kinase 1 Overexpression Lysate
Publications
Read Publication using
NB120-10524 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10 mM PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Concentration
2.0 mg/ml
Purity
Protein A or G purified

Alternate Names for DAP Kinase 1 [p Ser308] Antibody (DKPS308) - BSA Free

  • DAP Kinase 1
  • DAPK
  • DAPK1
  • DAPKDAP kinase 1
  • death-associated protein kinase 1
  • DKFZp781I035
  • EC 2.7.11
  • EC 2.7.11.1

Background

DAPK1 (Death-associated protein kinase 1) is a calmodulin dependent serine/threonine serine kinase which functions as a positive mediator of gamma-interferon induced programmed cell death. DAPK1 expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlates with high rates of metastasis. The loss of DAPK expression provides a link between suppression of apoptosis and metastasis. DAPK1 is thought be involved in an early apoptotic checkpoint which eliminates premalignant cells from cancer formation. Studies in bladder cancer patients have also shown that hypermethylation of DAPK1 correlates to high recurrence rates and thus DAPK1 may be used as a prognostic marker. DAPK1 is also reportedly a molecular regulator of neuronal death in epilepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DAP Kinase 1 Antibody (NB120-10524)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Product General Protocols

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Video Protocols

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FAQs for DAP Kinase 1 Antibody (NB120-10524) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DAPK1
Entrez
Uniprot