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Cytokeratin 13 Antibody (KS-1A3)

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Immunohistochemistry-Paraffin: Cytokeratin 13 Antibody (KS-1A3) [NBP1-22777] - Formalin fixed paraffin embedded human tonsils.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC
Clone
KS-1A3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Cytokeratin 13 Antibody (KS-1A3) Summary

Immunogen
Cultured A431 cells from a human epidermoid carcinoma of the vulva.
Localization
Cytoplasmic
Specificity
This is specific to a 54 kD protein. Cytokeratin 13 belongs to the type A (acidic) subfamily of low molecular weight cytokeratins and exists in combination with cytokeratin 4. Cytokeratin 13 is expressed in major components of squamous, non-keratinized epithelium, transitional epithelium, and myoepithelium. This antibody is useful for identifying carcinomas of trachea, sweat glands, bladder, extocervix, tongue, esophagus, anal canal, and the basal layer of keratinized epidermis.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KRT13
Purity
Ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:25-1:100
  • Immunohistochemistry-Paraffin 1:25-1:100
Application Notes
IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.
Publications
Read Publications using
NBP1-22777 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Ascites
Preservative
0.05% Sodium Azide
Purity
Ascites

Alternate Names for Cytokeratin 13 Antibody (KS-1A3)

  • CK13
  • CK-13
  • cytokeratin 13
  • Cytokeratin-13
  • K13cytokeratin-13
  • keratin 13
  • keratin, type I cytoskeletal 13
  • keratin-13
  • MGC161462
  • MGC3781

Background

Cytokeratin 13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cytokeratin 13 Antibody (NBP1-22777)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: FLOW, ICC/IF.


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FLOW
(1)
ICC/IF
(1)
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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Cytokeratin 13 Antibody (NBP1-22777). (Showing 1 - 1 of 1 FAQs).

  1. How much azide was added to NBP1-22777 (Cytokeratin 13 Antibody/KS-1A3)?
    • The sodium azide concentration for NBP1-22777 is 0.05%

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KRT13