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csl/RBPJK Antibody

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Immunocytochemistry/Immunofluorescence: csl/RBPJK Antibody [NBP2-56071] - Staining of human cell line A-431 shows localization to nucleoplasm.
Immunocytochemistry/ Immunofluorescence: csl/RBPJK Antibody [NBP2-56071] - Staining of human cell line A-431 shows localization to nucleoplasm.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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csl/RBPJK Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS
Predicted Species
Mouse (97%), Rat (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RBPJ
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
csl/RBPJK Recombinant Protein Antigen (NBP2-56071PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for csl/RBPJK Antibody

  • CBF1
  • CBF-1
  • CSL
  • H-2K binding factor-2
  • IGKJRB1
  • IGKJRB1RBPSUHCBF1
  • IGKJRBRBP-J kappa
  • immunoglobulin kappa J region recombination signal binding protein 1
  • J kappa-recombination signal-binding protein
  • KBF2
  • RBPJ
  • RBP-JK
  • RBPJKMGC61669
  • RBP-Jrecombining binding protein suppressor of hairless (Drosophila)
  • RBPSUH
  • recombination signal binding protein for immunoglobulin kappa J region
  • recombining binding protein suppressor of hairless
  • Renal carcinoma antigen NY-REN-30
  • SUH
  • suppressor of hairless homolog

Background

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Bioinformatics

Gene Symbol RBPJ