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CSE1L/CAS/Exportin-2 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, BvSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-79803AF350
Alexa Fluor 405
NB100-79803AF405
Alexa Fluor 488
NB100-79803AF488
Alexa Fluor 532
NB100-79803AF532
Alexa Fluor 594
NB100-79803AF594
Alexa Fluor 647
NB100-79803AF647
Alexa Fluor 700
NB100-79803AF700
Alexa Fluor 750
NB100-79803AF750
Allophycocyanin
NB100-79803APC
Biotin
NB100-79803B
DyLight 350
NB100-79803UV
DyLight 405
NB100-79803V
DyLight 488
NB100-79803G
DyLight 550
NB100-79803R
DyLight 594
NB100-79803DL594
DyLight 650
NB100-79803C
DyLight 680
NB100-79803FR
DyLight 755
NB100-79803IR
FITC
NB100-79803F
HRP
NB100-79803H
Janelia Fluor 525
NB100-79803JF525
Janelia Fluor 549
NB100-79803JF549
Janelia Fluor 585
NB100-79803JF585
Janelia Fluor 635
NB100-79803JF635
Janelia Fluor 646
NB100-79803JF646
Janelia Fluor 669
NB100-79803JF669
PE
NB100-79803PE
PerCP
NB100-79803PCP
Unconjugated
NB100-79803
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CSE1L/CAS/Exportin-2 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
The immunogen recognized by this antibody maps to a region between residues 1 and 50 of human Chromosome Segregation-1 using the numbering given in entry NP_001307.2 (GeneID 1434).
Predicted Species
Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CSE1L
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CSE1L/CAS/Exportin-2 Antibody [CoraFluor™ 1]

  • CAS
  • CASMGC117283
  • Cellular apoptosis susceptibility protein
  • chromosome segregation 1 (yeast homolog)-like
  • Chromosome segregation 1-like protein
  • CSE1 chromosome segregation 1-like (yeast)
  • CSE1
  • CSE1L
  • exp2
  • exportin-2
  • Importin-alpha re-exporter
  • MGC130037
  • XPO2
  • XPO2MGC130036

Background

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSE1L