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CRMP1 Antibody - BSA Free

Images

 
Western Blot: CRMP1 Antibody - BSA Free [NBP1-76651] - Western blot analysis of CRMP1 in human brain tissue lysate with CRMP1 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry: CRMP1 Antibody - BSA Free [NBP1-76651] - Immunohistochemistry of CRMP in human brain tissue with CRMP antibody at 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: CRMP1 Antibody - BSA Free [NBP1-76651] - Immunofluorescence of CRMP1 in Human Brain cells with CRMP1 antibody at 10 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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CRMP1 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human CRMP1. The immunogen is located within the last 50 amino acids of CRMP1. Amino Acid Squence: GAQIDDNNPRRTGHR
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRMP1
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 10 ug/ml
  • Immunohistochemistry 2 ug/ml
  • Immunohistochemistry-Paraffin 2 ug/ml
  • Western Blot 0.5-2 ug/ml
Control Peptide
CRMP1 Peptide (NBP1-76651PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for CRMP1 Antibody - BSA Free

  • collapsin response mediator protein 1DRP1
  • CRMP-1
  • dihydropyrimidinase-like 1
  • dihydropyrimidinase-related protein 1
  • DPYSL1DRP-1dihydropyrimidinase related protein-1
  • ULIP3
  • ULIP-3
  • Unc-33-like phosphoprotein 3

Background

Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CRMP1
Uniprot