Creatine kinase MT 1B Antibody - Azide and BSA Free

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.

Showing Publication 1 - 1 of 1.

Publication using NBP3-05655	Applications	Species
Ht Hall C, Lanis JM, Dowdell AS et al. Fundamental role for the creatine kinase pathway in protection from murine colitis Mucosal immunology 2023-09-14 [PMID: 37716510] (WB, Mouse)	WB	Mouse

Array NBP3-05655

• Creatine kinase MT 1B Antibodies
• Creatine kinase MT 1B ELISA Kits
• Creatine kinase MT 1B Lysate
• Creatine kinase MT 1B Protein