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Common gamma Chain/IL-2 R gamma Antibody (633162) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
633162
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
FAB2842V-100UG
Alexa Fluor 488
FAB2842G-100UG
Alexa Fluor 532
FAB2842X
Alexa Fluor 594
FAB2842T-100UG
Alexa Fluor 647
FAB2842R-100UG
Alexa Fluor 700
FAB2842N-100UG
Alexa Fluor 750
FAB2842S-100UG
Allophycocyanin
FAB2842A
Allophycocyanin/Cy7
FAB2842APCCY7
Biotin
FAB2842B
CoraFluor 1
FAB2842CL1
DyLight 350
FAB2842D
DyLight 405
FAB2842E
DyLight 488
FAB2842K
DyLight 550
FAB2842L
DyLight 594
FAB2842M
DyLight 650
FAB2842W
DyLight 680
FAB2842Y
DyLight 755
FAB2842Z
HRP
FAB2842H
Janelia Fluor 525
FAB2842JF525
Janelia Fluor 549
FAB2842I
Janelia Fluor 646
FAB2842J
Janelia Fluor 669
FAB2842JF669
PE/Atto594
FAB2842PEATT594
PE/Cy5.5
FAB2842PECY55
PE/Cy7
FAB2842PECY7
PerCP
FAB2842C
Unconjugated
MAB2842
mFluor Violet 450 SE
FAB2842MFV450
mFluor Violet 500 SE
FAB2842MFV500
mFluor Violet 610 SE
FAB2842MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2842
Carrier Free
FAB2842A
Carrier Free
MAB2842
Carrier Free
MAB2842-SP
Carrier Free
FAB2842V-100UG
Carrier Free
FAB2842T-100UG
Carrier Free
FAB2842S-100UG
Carrier Free
FAB2842R-100UG
Carrier Free
FAB2842N-100UG
Carrier Free
FAB2842G-100UG
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Common gamma Chain/IL-2 R gamma Antibody (633162) [Alexa Fluor® 350] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf21-derived recombinant human Common gamma Chain/IL-2 gamma
Leu23-Asn254
Accession # P31785
Specificity
Detects human Common gamma Chain/IL-2 R gamma in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rhIL-2 R beta , rhIL-15 R alpha , recombinant mouse IL-2 R gamma , or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80% cross-reactivity with recombinant human IL-2 R beta , 50% cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha , and no cross-reactivity with rhIL-2 R alpha is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
IL2RG
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Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Common gamma Chain/IL-2 R gamma Antibody (633162) [Alexa Fluor® 350]

  • CD132 antigen
  • CD132
  • CIDX
  • combined immunodeficiency, X-linked
  • common cytokine receptor gamma chain
  • Common gamma Chain
  • common gamma-chain
  • cytokine receptor common subunit gamma
  • gamma(c)
  • IL-2 R gamma
  • IL-2 receptor subunit gamma
  • IL2R gamma
  • IL-2R subunit gamma
  • IL2RG
  • IL-2RG
  • IMD4
  • interleukin 2 receptor, gamma
  • Interleukin-2 receptor subunit gamma
  • P64
  • SCIDX
  • SCIDX1
  • severe combined immunodeficiency

Background

The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid protein consisting of a 22 aa signal sequence, a 232 aa extracellular domain, a 29 aa transmembrane domain and an 86 aa cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL‑2 with any appreciable affinity, it is required for IL-2 receptor signaling. Besides IL-2, the gamma  chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. IL-2 R gamma has been designated the common gamma chain ( gamma c). The site of molecular defects in X-linked SCID (severe combined immunodeficiency) has been mapped to the IL-2 R gamma gene.

  1. Minami, Y. et al. (1993) Annu. Rev. Immunol. 11:245.
  2. Noguchi, M. et al. (1993) Science 262:1877.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IL2RG
Uniprot