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COMMD1 Antibody (2A12)

 (11 Publications)
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Western Blot: COMMD1 Antibody (2A12) [H00150684-M01] - COMMD1 monoclonal antibody (M01), clone 2A12 Analysis of COMMD1 expression in HeLa.
Western Blot: COMMD1 Antibody (2A12) [H00150684-M01] - COMMD1 monoclonal antibody (M01), clone 2A12 Analysis of COMMD1 expression in HeLa.
Western Blot: COMMD1 Antibody (2A12) [H00150684-M01] - Analysis of COMMD1 expression in transfected 293T cell line by COMMD1 monoclonal antibody (M01), clone 2A12.Lane 1: COMMD1 transfected lysate(21.2 KDa).Lane 2: ...read more
Immunoprecipitation: COMMD1 Antibody (2A12) [H00150684-M01] - Analysis of COMMD1 transfected lysate using anti-COMMD1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with COMMD1 MaxPab rabbit ...read more
ELISA: COMMD1 Antibody (2A12) [H00150684-M01] - Detection limit for recombinant GST tagged COMMD1 is approximately 0.03ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clone
2A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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COMMD1 Antibody (2A12) Summary

Immunogen
COMMD1 (AAH22046.1, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAAGELEGGKPLSGLLNALAQDTFHGYPGITEELLRSQLYPEVPPEEFRPFLAKMRGILKSIASADMDFNQLEAFLTAQTKKQGGITSDQAAVISKFWKSHKTKIRESLMNQSRWNSGLRGLSWRVDGKSQSRHSAQIHTPVAIIELELGKYGQESEFLCLEFDEVKVNQILKTLSEVEESISTLISQPN
Specificity
COMMD1 - copper metabolism (Murr1) domain containing 1
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
COMMD1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot 1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA. Use in ICC/IF was reported in scientific literature (PMID: 18795889).
Publications
Read Publications using H00150684-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for COMMD1 Antibody (2A12)

  • C2orf5
  • COMM domain-containing protein 1
  • COMMD1
  • copper metabolism (Murr1) domain containing 1
  • copper metabolism gene MURR1
  • MGC27155
  • MURR1
  • MURR1chromosome 2 open reading frame 5 (MURR1)
  • Protein Murr1

Background

COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al.,2005 (PubMed 16267171)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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COMMD1 Antibody
(2A12)
H00150684-M01
COMMD1 Antibody (2A12)
Species: Hu
Applications: WB, ELISA, IP

Publications for COMMD1 Antibody (H00150684-M01)(11)

We have publications tested in 2 applications: IP, WB.


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Showing Publications 1 - 10 of 11. Show All 11 Publications.
Publications using H00150684-M01 Applications Species
Hellen D, Julio M, Soledad A et al. The Anticancer Peptide CIGB-552 Exerts Anti-Inflammatory and Anti-Angiogenic Effects through COMMD1. Molecules. 2020-12-31 [PMID: 33396282]
O'Hara A, Simpson J, Morin P et al. P300-mediated acetylation of COMMD1 regulates its stability and the ubiquitination/nucleolar translocation of NF-kB/RelA. J Cell Sci. 2014-07-29 [PMID: 25074812]
Schilling D, Bayer C, Li W et al. Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1alpha. PLoS One. 2012-02-07 [PMID: 22347438]
Drevillon L, Tanguy G, Hinzpeter A et al. COMMD1-Mediated Ubiquitination Regulates CFTR Trafficking. PLoS One. 2011-03-31 [PMID: 21483833]
Vonk WI, Wijmenga C, Berger R et al. Cu/Zn superoxide dismutase maturation and activity are regulated by COMMD1. J Biol Chem. 2010-07-01 [PMID: 20595380]
Weiss KH, Lozoya JC, Tuma S et al. Copper-Induced Translocation of the Wilson Disease Protein ATP7B Independent of Murr1/COMMD1 Rab7. Am J Pathol;173(6):1783-1794. 2008-12-01 [PMID: 18974300]
Burkhead JL, Morgan CT, Shinde U et al. COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with PtdIns(4,5)p2. J Biol Chem;284(1):696-707. 2009-01-02 [PMID: 18940794]
Maine GN, Mao X, Muller PA et al. COMMD1 expression is controlled by critical residues that determine XIAP binding. Biochem J 2009-01-15 [PMID: 18795889] (IP, WB) IP, WB
Huang Y, Wu M, Li HY. Tumor suppressor ARF promotes non-classic proteasomal independent polyubiquitination of COMMD1. J Biol Chem;283(17):11453-60. 2008-04-25 [PMID: 18305112]
de Bie P, van de Sluis B, Burstein E et al. Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 reduced stability of ATP7B. Gastroenterology;133(4):1316-26. 2007-10-01 [PMID: 17919502]
Show All 11 Publications.

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Bioinformatics

Gene Symbol COMMD1
Entrez
OMIM
Uniprot