Cofilin Antibody (1A1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Cofilin is a small phosphoinositide sensitive, actin binding protein capable of depolymerizing actin filaments in vitro. Under certain conditions, it fragments the filaments and accelerates actin subunit dissociation from their pointed (minus) ends. Cofilin binds stoichiometrically to monomeric G-actin and to actin protomers in filaments in an apparent pH-dependent, Ca2+- independent manner. Cofilin intercalates between longitudinally associated actin monomers within the filament and distorts its helical twist. Cofilin is ubiquitous in tissues of eukaryotes and is especially abundant in neuronal tissues. It is essential for viability and is important for many cellular processes involving actin remodeling such as motility at the leading edge of cells, polarized cell growth, endocytosis, phagocytosis, cellular activation, cytokinesis, and pathogen intracellular motility

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IF/IHC.

Showing Publications 1 - 4 of 4.

Publications using H00001072-M04	Applications	Species
Chang YF, Chao CH, Lin LY et al. Determination of urine cofilin-1 level in acute kidney injury using a high-throughput localized surface plasmon-coupled fluorescence biosensor. J Biomed Opt. 2014-01-01 [PMID: 23788282]
Franciosi L, Govorukhina N, Fusetti F et al. Proteomic analysis of human Epithelial Lining Fluid by microfluidics-based nanoLC-MS/MS: a feasibility study. Electrophoresis 2013-09-01 [PMID: 23712570] (IF/IHC, Human)	IF/IHC	Human
Sakai A, Otani M, Miyamoto A et al. Identification of phosphorylated serine-15 and -82 residues of HSPB1 in 5-fluorouracil- resistant colorectal cancer cells by proteomics. Journal of Proteomics. 2011-01-01 [PMID: 21989268]
Nishimura S, Tsuda H, Kataoka F et al. Overexpression of cofilin 1 can predict progression-free survival in patients with epithelial ovarian cancer receiving standard therapy. Hum Pathol. 2011-01-13 [PMID: 21237490]

Array H00001072-M04

• Cofilin Antibodies
• Cofilin ELISA Kits
• Cofilin Lysate
• Cofilin Proteins