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Chromogranin A Antibody (LK2H10) [Alexa Fluor® 647]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Pm, Gp(-), Rb(-), Sh(-)Species Glossary
Applications Flow, IHC, CyTOF-ready
Clone
LK2H10
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 647

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-34672AF350
Alexa Fluor 405
NBP2-34672AF405
Alexa Fluor 488
NBP2-34672AF488
Alexa Fluor 532
NBP2-34672AF532
Alexa Fluor 594
NBP2-34672AF594
Alexa Fluor 700
NBP2-34672AF700
Alexa Fluor 750
NBP2-34672AF750
Allophycocyanin
NBP2-34672APC
Biotin
NBP2-34672B
DyLight 350
NBP2-34672UV
DyLight 405
NBP2-34672V
DyLight 488
NBP2-34672G
DyLight 550
NBP2-34672R
DyLight 594
NBP2-34672DL594
DyLight 650
NBP2-34672C
DyLight 680
NBP2-34672FR
DyLight 755
NBP2-34672IR
FITC
NBP2-34672F
HRP
NBP2-34672H
Janelia Fluor 549
NBP2-34672JF549
Janelia Fluor 646
NBP2-34672JF646
PE
NBP2-34672PE
PerCP
NBP2-34672PCP
Unconjugated
NBP2-34672-0.1mg
mFluor Violet 450 SE
NBP2-34672MFV450
mFluor Violet 500 SE
NBP2-34672MFV500
mFluor Violet 610 SE
NBP2-34672MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-34672-0.1mg
IHC-Prediluted
NBP2-44767
Azide and BSA Free
NBP2-34672-0.1mg
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Chromogranin A Antibody (LK2H10) [Alexa Fluor® 647] Summary

Immunogen
Human pheochromocytoma (Uniprot: P10645)
Localization
Finely granular cytoplasmic
Marker
Neuroendocrine Marker
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CHGA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin

Reactivity Notes

Does not react with Guinea Pig, Sheep or Rabbit.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Chromogranin A Antibody (LK2H10) [Alexa Fluor® 647]

  • betagranin (N-terminal fragment of chromogranin A)
  • Betagranin
  • Catestatin
  • CGA
  • CHGA
  • Chromofungin
  • chromogranin A (parathyroid secretory protein 1)
  • Chromogranin A
  • chromogranin-A
  • Pancreastatin
  • Parastatin
  • Parathyroid Secretory Protein 1
  • Pituitary Secretory Protein I
  • SP-I

Background

Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neuroendocrine cells. CgA is believed to play a role in targeting peptide hormones and neurotransmitters to granules of the regulated pathways and inhibit hormone and neurotransmitter release. Also, the widespread distribution of CgA has made the measurement of circulating immunoreactive CgA a valuable tool in the diagnosis of neuroendocrine neoplasia, and CgA immunohistochemistry can help to identify the neuroendocrine nature of tumors. The N-terminal domain of CgA inhibits tumor necrosis factor a (TNFa) induced gap formation in human umbilical venous endothelial cells. CgA levels which reflect neuroendocrine differentiation of prostatic carcinoma may have a diagnostic, therapeutic and prognostic role in the management of prostate cancer patients.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Chromogranin A Antibody (NBP2-34672AF647). (Showing 1 - 1 of 1 FAQ).

  1. I have following question about antibodies against Chromogranin A. Your products list the species but canine is not included. Does it mean that the products cannot be used on canine tissues?
    • When we do not list a species, it means we have not tested an antibody to work with those samples. If we test an antibody and find that it does not work, we will list the species with a minus sign. Unfortunately, we haven't tried these abs on canine tissues and they may work, but we cannot guarantee it. If you would like to purchase one to try, you will be eligible for the Innovators Reward Program.

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Bioinformatics

Gene Symbol CHGA