CDNF Antibody - BSA Free

The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 3 applications: Immunohistochemistry-Frozen, WB, Western Blot.

Showing Publications 1 - 2 of 2.

Publications using NBP1-76834	Applications	Species
Xu Q, Yang S, Wu F et al. Congrong Shujing Granule-Induced GRP78 Expression Reduced Endoplasmic Reticulum Stress and Neuronal Apoptosis in the Midbrain in a Parkinson's Disease Rat Model Evidence-Based Complementary and Alternative Medicine 2020-09-30 [PMID: 33062012] (Western Blot, Immunohistochemistry-Frozen)	Western Blot, Immunohistochemistry-Frozen
Lin Y, Tang L, Huang P et al. Mechanisms of Cong Rong Shu Jing Compound Effects on Endoplasmic Reticulum Stress in a Rat Model of Parkinson’s Disease Evidence-Based Complementary and Alternative Medicine 2020-05-14 [PMID: 32508943] (WB, Rat)	WB	Rat

Array NBP1-76834

• CDNF Antibodies
• CDNF ELISA Kits
• CDNF Lysate
• CDNF Proteins
• CDNF Proteins and Enzymes