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CD31/PECAM-1 Antibody (9G11) [Phycoerythrin]

Images

 
Human peripheral blood granulocytes were stained with Mouse Anti-Human CD31/PECAM-1 PE-conjugated Monoclonal Antibody (Catalog # FAB3567P, filled histogram) or isotype control antibody (Catalog # IC002P, open ...read more
THP-1 human acute monocytic leukemia cell line was stained with Mouse Anti-Human CD31/PECAM-1 PE-conjugated Monoclonal Antibody (Catalog # FAB3567P, filled histogram) or isotype control antibody (IC002P, open ...read more
CD31/PECAM-1 knockout THP-1 human acute monocytic leukemia cell line was stained with Mouse Anti-Human CD31/PECAM-1 PE-conjugated Monoclonal Antibody (Catalog # FAB3567P, filled histogram) or isotype control antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, KO
Clone
9G11
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

CD31/PECAM-1 Antibody (9G11) [Phycoerythrin] Summary

Immunogen
Activated HUVEC human umbilical vein endothelial cells
Specificity
Detects human CD31/PECAM‑1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) E‑Selectin, rhICAM-1, -2, -3, rhVCAM-1, or recombinant mouse VCAM-1 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PECAM1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
  • Knockout Validated 10 uL/10^6 cells
Publications
Read Publications using
FAB3567P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD31/PECAM-1 Antibody (9G11) [Phycoerythrin]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • EndoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet endothelial cell adhesion molecule-1
  • platelet/endothelial cell adhesion molecule

Background

The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD31/PECAM-1 Antibody (FAB3567P)(12)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 5 applications: Bioassay, Cell Selection, Flow Cytometry, ICC, IHC.


Filter By Application
Bioassay
(1)
Cell Selection
(1)
Flow Cytometry
(6)
ICC
(2)
IHC
(1)
All Applications
Filter By Species
Human
(10)
All Species
Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using FAB3567P Applications Species
Masuda, S;Matsuura, K;Shimizu, T; GATA6 regulates anti-angiogenic properties in human cardiac fibroblasts via modulating LYPD1 expression Regenerative therapy 2023-06-01 [PMID: 37251737] (Bioassay, Human) Bioassay Human
Y Basmaeil, E Bahattab, A Al Subayyi, HB Kulayb, M Alrodayyan, M Abumaree, T Khatlani Decidua Parietalis Mesenchymal Stem/Stromal Cells and Their Secretome Diminish the Oncogenic Properties of MDA231 Cells In Vitro Cells, 2021-12-10;10(12):. 2021-12-10 [PMID: 34944000] (Flow Cytometry, Human) Flow Cytometry Human
A Inui, H Sekine, K Sano, I Dobashi, A Yoshida, K Matsuura, E Kobayashi, M Ono, T Shimizu Generation of a large-scale vascular bed for the in�vitro creation of three-dimensional cardiac tissue Regen Ther, 2019-10-22;11(0):316-323. 2019-10-22 [PMID: 31687425] (Flow Cytometry, Human) Flow Cytometry Human
Daniela Unterleuthner, Patrick Neuhold, Katharina Schwarz, Lukas Janker, Benjamin Neuditschko, Harini Nivarthi et al. Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer Angiogenesis 5/1/2020 [PMID: 31667643]
S Masuda, K Matsuura, T Shimizu Preparation of iPS cell-derived CD31+ endothelial cells using three-dimensional suspension culture Regen Ther, 2018-07-07;9(0):1-9. 2018-07-07 [PMID: 30525069] (Cell Selection, ICC, Human) Cell Selection, ICC Human
T Kryza, C Parent, J Pardessus, A Petit, J Burlaud-Ga, P Reverdiau, S Iochmann, V Labas, Y Courty, N Heuzé-Vour Human kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix Sci Rep, 2018-04-20;8(1):6331. 2018-04-20 [PMID: 29679011] (ICC, Human) ICC Human
Xiaoyu Xing, Zhiyuan Zhang, Liang Zhong, Guanqun Ju, Xiangyu Zou, Yingjian Zhu et al. Differentiation of human umbilical cord mesenchymal stem cells into steroidogenic cells in vitro Experimental and Therapeutic Medicine 12/1/2016 [PMID: 28105086]
Norton , Kerri-An, Han , Zheyi, Popel , Aleksand, Pandey , Niranjan Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells. Onco Targets Ther, 2014-09-09;7(0):1571-82. 2014-09-09 [PMID: 25228815] (Flow Cytometry, Human) Flow Cytometry Human
Kryza T, Achard C, Parent C, Marchand-Adam S, Guillon-Munos A, Iochmann S, Korkmaz B, Respaud R, Courty Y, Heuze-Vourc'h N Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway. FASEB J, 2013-11-13;28(2):740-51. 2013-11-13 [PMID: 24225148] (IHC, Human) IHC Human
Frassanito M, Rao L, Moschetta M, Ria R, di Marzo L, De Luisi A, Racanelli V, Catacchio I, Berardi S, Basile A, Menu E, Ruggieri S, Nico B, Ribatti D, Fumarulo R, Dammacco F, Vanderkerken K, Vacca A Bone marrow fibroblasts parallel multiple myeloma progression in patients and mice: in vitro and in vivo studies. 2013-09-02;0(0):. 2013-09-02 [PMID: 23995611] (Flow Cytometry, Human) Flow Cytometry Human
Show All 12 Publications.

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Secondary Antibodies

 

Isotype Controls

Additional CD31/PECAM-1 Products

Blogs on CD31/PECAM-1.


  Read full blog post.

The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...  Read full blog post.

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Bioinformatics

Gene Symbol PECAM1