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CD31/PECAM-1 Antibody (9G11) [Allophycocyanin]

Images

 
Human peripheral blood granulocytes were stained with Mouse Anti-Human CD31/PECAM-1 APC-conjugated Monoclonal Antibody (Catalog # FAB3567A, filled histogram) or isotype control antibody (Catalog # IC002A, open ...read more
THP-1 human acute monocytic leukemia cell line was stained with Mouse Anti-Human CD31/PECAM-1 APC-conjugated Monoclonal Antibody (Catalog # FAB3567A, filled histogram) or isotype control antibody (IC002A, open ...read more
CD31/PECAM-1 knockout THP-1 human acute monocytic leukemia cell line was stained with Mouse Anti-Human CD31/PECAM-1 APC-conjugated Monoclonal Antibody (Catalog # FAB3567A, filled histogram) or isotype control antibody ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, KO
Clone
9G11
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

CD31/PECAM-1 Antibody (9G11) [Allophycocyanin] Summary

Immunogen
Activated HUVEC human umbilical vein endothelial cells
Specificity
Detects human CD31/PECAM‑1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) E‑Selectin, rhICAM-1, -2, -3, rhVCAM-1, or recombinant mouse VCAM-1 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PECAM1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
  • Knockout Validated
Reviewed Applications
Read 1 Review rated 3
using
FAB3567A in the following applications:

Publications
Read Publications using
FAB3567A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD31/PECAM-1 Antibody (9G11) [Allophycocyanin]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • EndoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet endothelial cell adhesion molecule-1
  • platelet/endothelial cell adhesion molecule

Background

The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD31/PECAM-1 Antibody (FAB3567A)(10)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(5)
ICC
(2)
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Filter By Species
Human
(7)
All Species
Showing Publications 1 - 10 of 10.
Publications using FAB3567A Applications Species
Hall, E;Alderfer, L;Neu, E;Saha, S;Johandes, E;Haas, DM;Haneline, LS;Hanjaya-Putra, D; The Effects of Preeclamptic Milieu on Cord Blood Derived Endothelial Colony-Forming Cells bioRxiv : the preprint server for biology 2023-12-05 [PMID: 38105991] (Flow Cytometry, Human) Flow Cytometry Human
JP Ribeiro, RMA Domingues, PS Babo, LP Nogueira, JE Reseland, RL Reis, M Gomez-Flor, ME Gomes Highly elastic and bioactive bone biomimetic scaffolds based on platelet lysate and biomineralized cellulose nanocrystals Carbohydrate polymers, 2022-05-20;292(0):119638. 2022-05-20 [PMID: 35725198] (ICC, Human) ICC Human
SF Mause, E Ritzel, A Deck, F Vogt, EA Liehn Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis International Journal of Molecular Sciences, 2022-01-14;23(2):. 2022-01-14 [PMID: 35055054] (ICC, Human) ICC Human
Marco Campisi, Shriram K. Sundararaman, Sarah E. Shelton, Erik H. Knelson, Navin R. Mahadevan, Ryohei Yoshida et al. Tumor-Derived cGAMP Regulates Activation of the Vasculature Frontiers in Immunology 9/4/2020 [PMID: 33013881]
CH Chou, M Modo Characterization of gene expression changes in human neural stem cells and endothelial cells modeling a neurovascular microenvironment Brain Res. Bull., 2020-02-21;158(0):9-19. 2020-02-21 [PMID: 32092433] (Flow Cytometry, Human) Flow Cytometry Human
F Lopes-Coel, F Silva, S Gouveia-Fe, C Martins, N Lopes, G Domingues, C Brito, AM Almeida, SA Pereira, J Serpa Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis Cells, 2020-01-01;9(1):. 2020-01-01 [PMID: 31906296] (Flow Cytometry, Human) Flow Cytometry Human
Erika Moravcikova, E. Michael Michael Meyer, Mirko Corselli, Vera S. Donnenberg, Albert D. Donnenberg Proteomic Profiling of Native Unpassaged and Culture‐Expanded Mesenchymal Stromal Cells (MSC) Cytometry Part A 9/1/2018 [PMID: 30211967]
McIver Z, Melenhorst J, Wu C, Grim A, Ito S, Cho I, Hensel N, Battiwalla M, Barrett A Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant. Haematologica, 2012-10-12;98(3):346-52. 2012-10-12 [PMID: 23065508] (Flow Cytometry, Human) Flow Cytometry Human
Ludovic Zimmerlin, Albert D. Donnenberg, J. Peter Rubin, Per Basse, Rodney J. Landreneau, Vera S. Donnenberg Regenerative Therapy and Cancer: In Vitro and In Vivo Studies of the Interaction Between Adipose-Derived Stem Cells and Breast Cancer Cells from Clinical Isolates Tissue Engineering Part A 1/1/2011 [PMID: 20673000]
Xiong YQ, Sun HC, Zhang W Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells. Clin. Cancer Res., 2009-07-28;15(15):4838-46. 2009-07-28 [PMID: 19638466] (Flow Cytometry, Human) Flow Cytometry Human

Review for CD31/PECAM-1 Antibody (FAB3567A) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using FAB3567A:
Filter by Applications
ICC
(1)
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Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
  3
reviewed by:
Verified Customer
ICC Human 01/23/2015
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Summary

ApplicationImmunocytochemistry
Sample TestedSee PMID: 23200853
SpeciesHuman

Product General Protocols

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FAQs for CD31/PECAM-1 Antibody (FAB3567A) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CD31/PECAM-1 Products

Blogs on CD31/PECAM-1.


  Read full blog post.

The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...  Read full blog post.

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Verified Customer
01/23/2015
Application: ICC
Species: Human

Bioinformatics

Gene Symbol PECAM1