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CCR7 Antibody (150503) [Phycoerythrin]

Images

 
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A) and either (A) Mouse Anti-Human CCR7 PE-conjugated Monoclonal Antibody (Catalog # ...read more
The specificity of Mouse Anti-Human CCR7 Clone 150503 was demonstrated by its ability to react with (A) HEK293 human embryonic kidney cell line transfected with human CCR7 and not react with (B) irrelevant HEK293 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
150503
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

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CCR7 Antibody (150503) [Phycoerythrin] Summary

Additional Information
Clone 150503 was used by HLDA to establish CD designation
Immunogen
Human CCR7 transfectants
Met1-Pro378
Accession # AAA58615
Specificity
Detects human CCR7.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CCR7
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 4 Reviews rated 4.5
using
FAB197P in the following application:

Publications
Read Publications using
FAB197P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR7 Antibody (150503) [Phycoerythrin]

  • BLR2
  • BLR2C-C chemokine receptor type 7
  • C-C CKR-7
  • CC-CKR-7
  • CCR7
  • CCR-7
  • CD197 antigen
  • CD197
  • CDw197
  • CDw197CC chemokine receptor 7
  • chemokine (C-C motif) receptor 7
  • CMKBR7
  • CMKBR7chemokine (C-C) receptor 7
  • EBI1
  • EBI1EBV-induced G protein-coupled receptor 1
  • EBV-induced G-protein coupled receptor 1
  • Epstein-Barr virus induced gene 1
  • Epstein-Barr virus induced G-protein coupled receptor
  • Epstein-Barr virus-induced G-protein coupled receptor 1
  • EVI1
  • lymphocyte-specific G protein-coupled peptide receptor
  • MIP-3 beta receptor

Background

CCR7 (Chemokine Receptor 7; also CD197) is a 7 transmembrane (7TM) G protein-coupled chemokine receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine. CCL19 and CCL21 are constitutively expressed by high endothelial venule epithelial cells or fibroblastic reticular cells in secondary lymphoid organs. CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK cells, and B cells following inflammatory stimulation. Its expression enables the function of immune cell trafficking to and retention in regional lymph nodes for expansion of the adaptive immune response. Human CCR7 shares 87% amino acid sequence identity with mouse CCR7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR7 Antibody (FAB197P)(71)

We have publications tested in 3 confirmed species: Human, Primate, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 2 applications: Flow Cytometry, ICC.


Filter By Application
Flow Cytometry
(60)
ICC
(2)
All Applications
Filter By Species
Human
(58)
Primate
(1)
Primate - Macaca mulatta (Rhesus Macaque)
(3)
All Species
Showing Publications 1 - 10 of 71. Show All 71 Publications.
Publications using FAB197P Applications Species
Sadeghi, L;Wright, APH; GSK-J4 Inhibition of KDM6B Histone Demethylase Blocks Adhesion of Mantle Cell Lymphoma Cells to Stromal Cells by Modulating NF-?B Signaling Cells 2023-08-06 [PMID: 37566089] (ICC, Human) ICC Human
Jani Huuhtanen, Henna He Kasanen, Katriina Peltola, Tapio Lönnberg, Virpi Glumoff, Oscar Brück et al. Single-cell characterization of anti–LAG-3 and anti–PD-1 combination treatment in patients with melanoma Journal of Clinical Investigation 3/15/2023 [PMID: 36719749]
Jani Huuhtanen, Mette Ilander, Bhagwan Yadav, Olli M.J. Dufva, Hanna Lähteenmäki, Tiina Kasanen et al. IFN-alpha with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia Journal of Clinical Investigation 9/1/2022 [PMID: 36047494]
S Koido, S Horiuchi, S Kan, T Bito, Z Ito, K Uchiyama, M Saruta, N Sato, T Ohkusa The stimulatory effect of fusobacteria on dendritic cells under aerobic or anaerobic conditions Oncogene, 2022-06-23;12(1):10698. 2022-06-23 [PMID: 35739324] (ICC, Human) ICC Human
T Mateu-Albe, A Marcos-Jim, S Wissmann, J Loscertale, F Terrón, JV Stein, C Muñoz-Call, C Cuesta-Mat Ibrutinib Does Not Impact CCR7-Mediated Homeostatic Migration in T-Cells from Chronic Lymphocytic Leukemia Patients Cancers, 2022-05-31;14(11):. 2022-05-31 [PMID: 35681706] (Flow Cytometry, Human) Flow Cytometry Human
I Del Molino, A Meeson, K Cooke, MI Malki, B Barron-Mil, JA Kirby, S Ali Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells Cancers, 2021-07-10;13(14):. 2021-07-10 [PMID: 34298676] (Flow Cytometry, Human) Flow Cytometry Human
T Hirama, S Tokita, M Nakatsugaw, K Murata, Y Nannya, K Matsuo, H Inoko, Y Hirohashi, S Hashimoto, S Ogawa, I Takemasa, N Sato, F Hata, T Kanaseki, T Torigoe Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch-repair-deficient colorectal cancer tissue JCI Insight, 2021-07-22;0(0):. 2021-07-22 [PMID: 34185709] (Flow Cytometry, Human) Flow Cytometry Human
D Kim, G Park, J Huuhtanen, S Lundgren, RK Khajuria, AM Hurtado, C Muñoz-Call, L Cardeñoso, V Gómez-Garc, TH Chen-Liang, S Eldfors, P Ellonen, S Hannula, M Kankainen, O Bruck, A Kreutzman, U Salmenniem, T Lönnberg, A Jerez, M Itälä-Reme, M Myllymäki, MAI Keränen, S Mustjoki Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease Nat Commun, 2020-05-07;11(1):2246. 2020-05-07 [PMID: 32382059] (Flow Cytometry, Human) Flow Cytometry Human
T Tyrinova, O Leplina, S Mishinov, M Tikhonova, E Dolgova, A Proskurina, V Stupack, S Bogachev, A Ostanin, E Chernykh Defective Regulation of Membrane TNF&alpha Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells Int J Mol Sci, 2020-04-21;21(8):. 2020-04-21 [PMID: 32326230] (Flow Cytometry, Human) Flow Cytometry Human
Yukari Kobayashi, Daisuke Yamada, Taketo Kawai, Yusuke Sato, Taro Teshima, Yuta Yamada et al. Different immunological effects of the molecular targeted agents sunitinib, everolimus and temsirolimus in patients with renal cell carcinoma International Journal of Oncology 2/4/2020 [PMID: 32319571]
Show All 71 Publications.

Reviews for CCR7 Antibody (FAB197P) (4) 4.54

Average Rating: 4.5
(Based on 4 reviews)
We have 4 reviews tested in 1 species: Human.

Reviews using FAB197P:
Filter by Applications
Flow
(4)
All Applications
Filter by Species
Human
(4)
All Species
Images Ratings Applications Species Date Details
  5
reviewed by:
Verified Customer
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 23168838
SpeciesHuman
  5
reviewed by:
Verified Customer
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 23168838
SpeciesHuman
  4
reviewed by:
Verified Customer
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 19041139
SpeciesHuman
  4
reviewed by:
Verified Customer
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 20884014
SpeciesHuman

Product General Protocols

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FAQs for CCR7 Antibody (FAB197P) (0)

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Recent Reviews

4.5
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2
4
2
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0
2
0
1
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Verified Customer
01/21/2015
Application: Flow
Species: Human

 
Verified Customer
01/21/2015
Application: Flow
Species: Human

 
Verified Customer
01/21/2015
Application: Flow
Species: Human

Bioinformatics

Gene Symbol CCR7
Uniprot