Ccd1/DIXDC1 Antibody

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Immunoprecipitation:[NBP3-29797]-Detection of human DIXDC1 by western blot of immunoprecipitates. Samples: Whole cell lysate from 293T cells. Antibodies: Affinity purified rabbit anti-DIXDC1 antibody used for IP at 6 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Ccd1/DIXDC1 Antibody Summary

Immunogen
Between 633 and 683
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DIXDC1
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for Ccd1/DIXDC1 Antibody

  • Ccd1
  • Coiled-coil protein DIX1
  • Coiled-coil-DIX1
  • DIX domain containing 1
  • DIX domain-containing protein 1
  • Dixdc1
  • Dixin
  • Kiaa1735
  • KIAA1735coiled-coil-DIX1

Background

DIXDC1 (DIX domain containing 1/Dixin) is a 683 amino acid protein. It positively regulates the Wnt signaling pathway by activating WNT3A via DVL2. It is expressed ubiquitously but has higher expression in skeletal and cardiac muscle. WNT3A signaling increases DIXDC1 protein levels by inhibiting its ubiquitination and subsequent degradation. DIXDC1 may play a role in breast cancer, breast carcinoma, endometrial cancer, epithelial neoplasia, schizophrenia, colon cancer, and neuroblastoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DIXDC1