Caveolin-1 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Caveolin-1 is a palmitoylated 22 kDa membrane-associated protein in caveolae which are cholesterol-rich invaginations in the plasma membrane involved in vesicular transport and the regulation of lipid rafts and signal transduction. Caveolin-1 expression is dysregulated during cancer progression and exhibits both positive and negative effects on tumor progression. The central region of Caveolin-1 (aa 105 - 125) is buried in the lipid layer, while the N- and C-terminal flanking regions are exposed to the cytoplasm and interact with many other proteins. Alternate splicing in human, mouse, and rat Caveolin-1 generates an isoform with a deletion of the
N-terminal 31 residues.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: Immunocytochemistry, Proximity Ligation Assay (PLA), Western Blot.

Showing Publications 1 - 5 of 5.

Publications using AF5736	Applications	Species
Hong, SG;Ashby, JW;Kennelly, JP;Wu, M;Chattopadhyay, E;Foreman, R;Tontonoz, P;Turowski, P;Gallagher-Jones, M;Mack, JJ; Polarized Mechanosensitive Signaling Domains Protect Arterial Endothelial Cells Against Inflammation bioRxiv : the preprint server for biology 2023-05-26 [PMID: 37292837] (Proximity Ligation Assay (PLA), Immunocytochemistry, Human)	Proximity Ligation Assay (PLA), Immunocytochemistry	Human
S. Kaya, Nadine Wiesmann, J. Goldschmitt, M. Krüger, B. Al-Nawas, J. Heider Differences in the expression of caveolin-1 isoforms in cancer-associated and normal fibroblasts of patients with oral squamous cell carcinoma Clinical Oral Investigations 10/1/2021 [PMID: 33774714]
S Saleem, S Tariq, I Aleem, Sadr-Ul Sh, M Tahseen, A Atiq, S Hassan, M Abu Bakar, S Khattak, AA Syed, AH Ahmad, M Hussain, MA Yusuf, C Sutton Proteomics analysis of colon cancer progression Clin Proteomics, 2019-12-28;16(0):44. 2019-12-28 [PMID: 31889941] (Western Blot, Human)	Western Blot	Human
T Tomono, K Yano, T Ogihara Snail-Induced Epithelial-to-Mesenchymal Transition Enhances P-gp-Mediated Multi Drug Resistance in HCC827 Cells J Pharm Sci, 2017-03-18;0(0):. 2017-03-18 [PMID: 28322937] (Western Blot, Human)	Western Blot	Human
Mini Aga, John M. Bradley, Rohan Wanchu, Yong-feng Yang, Ted S. Acott, Kate E. Keller Differential Effects of Caveolin-1 and -2 Knockdown on Aqueous Outflow and Altered Extracellular Matrix Turnover in Caveolin-Silenced Trabecular Meshwork Cells Investigative Opthalmology & Visual Science 9/2/2014 [PMID: 25103269]

Array AF5736

• Caveolin-1 Antibodies
• Caveolin-1 ELISA Kits
• Caveolin-1 Lysate
• Caveolin-1 Proteins