47.3 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publication using NBC1-18386 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 500 mM NaCl, 1 mM DTT, 50% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE
Alternate Names for Recombinant Human Casein Kinase 2 alpha His Protein
Casein Kinase 2 alpha
casein kinase 2, alpha 1 polypeptide
casein kinase II alpha 1 subunit
CK II alpha
CK2 catalytic subunit alpha
CK2A1
CK2A1casein kinase II subunit alpha
CKII
CSNK2A1
EC 2.7.11
EC 2.7.11.1
protein kinase CK2
Background
Protein Kinase Casein Kinase 2 (PKCK2, also called CK2) is a ubiquitous Ser/Thr kinase expressed in all eukaryotes. PKCK2 is a tetramer composed of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. It has been implicated in cell cycle control , DNA repair, regulation of the circadian rhythm, and other cellular processes. Recombinant human PKCK2, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.
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