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Capicua Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications ICC/IF, IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-59905AF350
Alexa Fluor 405
NB110-59905AF405
Alexa Fluor 488
NB110-59905AF488
Alexa Fluor 532
NB110-59905AF532
Alexa Fluor 594
NB110-59905AF594
Alexa Fluor 647
NB110-59905AF647
Alexa Fluor 700
NB110-59905AF700
Alexa Fluor 750
NB110-59905AF750
Allophycocyanin
NB110-59905APC
Biotin
NB110-59905B
CoraFluor 1
NB110-59905CL1
DyLight 350
NB110-59905UV
DyLight 405
NB110-59905V
DyLight 550
NB110-59905R
DyLight 594
NB110-59905DL594
DyLight 650
NB110-59905C
DyLight 680
NB110-59905FR
DyLight 755
NB110-59905IR
FITC
NB110-59905F
HRP
NB110-59905H
Janelia Fluor 525
NB110-59905JF525
Janelia Fluor 549
NB110-59905JF549
Janelia Fluor 585
NB110-59905JF585
Janelia Fluor 635
NB110-59905JF635
Janelia Fluor 646
NB110-59905JF646
Janelia Fluor 669
NB110-59905JF669
PE
NB110-59905PE
PerCP
NB110-59905PCP
Unconjugated
NB110-59905
mFluor Violet 450 SE
NB110-59905MFV450
mFluor Violet 500 SE
NB110-59905MFV500
mFluor Violet 610 SE
NB110-59905MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-59905
BSA Free
NB110-59905
BSA Free
NB110-59905SS
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Capicua Antibody [DyLight 488] Summary

Immunogen
The epitope recognized by this antibody maps to a region within residue 1150-1200 of human Capicua. [NP_055940.3]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CIC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Capicua Antibody [DyLight 488]

  • capicua homolog (Drosophila)
  • KIAA0306capicua (Drosophila) homolog
  • protein capicua homolog

Background

CIC, a human homolog of Drosophila capicua, encodes a high mobility group box transcription factor and is fused to a double homeodomain gene DUX4 as a result of a recurrent chromosomal translocation. It is involved in epidermal growth factor receptor (EGFR) signaling, developmental patterning, and cell fate. In humans, CIC may be involved in granule cell lineage, cerebellar development, and medulloblastoma tumorigenesis. Recent evidence indicates that CIC is involved in Spinocerebellar Ataxia Type 1 (SCA-1) where it interacts directly with the product of the SCA-1 gene Ataxin-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Capicua Antibody
[DyLight 488]
NB110-59905G
Capicua Antibody [DyLight 488]
Species: Hu, Mu, Rt, Ca
Applications: ICC/IF, IP, WB (-)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CIC