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CADPS Antibody

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Immunocytochemistry/Immunofluorescence: CADPS Antibody [NBP2-38871] - Staining of human cell line SK-MEL-30 shows localization to vesicles.
Immunocytochemistry/ Immunofluorescence: CADPS Antibody [NBP2-38871] - Staining of human cell line SK-MEL-30 shows localization to vesicles.
Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining of human kidney shows low expression as expected.
Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining of human pancreas shows strong cytoplasmic positivity in islets of Langerhans and subset of exocrine glandular cells.
Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining of human cerebral cortex shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: CADPS Antibody [NBP2-38871] - Staining in human cerebral cortex and kidney tissues using anti-CADPS antibody. Corresponding CADPS RNA-seq data are presented ...read more

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

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CADPS Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: SEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGS
Predicted Species
Rat (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CADPS
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
CADPS Protein (NBP2-38871PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for CADPS Antibody

  • Ca++-dependent secretion activator
  • CADPS1
  • Calcium-dependent activator protein for secretion 1
  • calcium-dependent secretion activator 1
  • CAPS-1
  • CAPS1Ca2+-dependent secretion activator
  • CAPSCa2+-dependent activator protein for secretion
  • KIAA1121Ca2+-regulated cytoskeletal protein

Background

CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CADPS Antibody
NBP2-38871
CADPS Antibody
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Applications: ICC/IF, IHC

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

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Array NBP2-38871

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Bioinformatics

Gene Symbol CADPS
Uniprot