C5L2/GPR77 Antibody (468705) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

C5L2, also known as GPR77, is a 45 kDa 7TM receptor that binds the complement proteins C3a, C4a, and C5a as well as the acylation stimulating peptide (ASP). C5L2 is expressed on various hematopoietic cells where it promotes complement-mediated inflammation. ASP binding to C5L2 on adipocytes triggers triglyceride synthesis and glucose uptake and inhibits lipolysis. Human C5L2 shares 60% amino acid sequence identity with mouse and rat C5L2.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Flow Cytometry.

Showing Publications 1 - 2 of 2.

Publications using MAB4729	Applications	Species
D A Verghese, M Demir, N Chun, M Fribourg, P Cravedi, I Llaudo, TM Woodruff, P Yadav, SA Lira, ME Medof, PS Heeger T Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell (T) Generation and T-Dependent Cardiac Allograft Survival J. Immunol., 2018-02-07;0(0):. 2018-02-07 [PMID: 29436411] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse
CM Karsten, AV Wiese, F Mey, J Figge, TM Woodruff, T Reuter, O Scurtu, A Kordowski, LN Almeida, D Briukhovet, KM Quell, J Sun, F Ender, I Schmudde, T Vollbrandt, Y Laumonnier, J Köhl Monitoring C5aR2 Expression Using a Floxed tdTomato-C5aR2 Knock-In Mouse J. Immunol., 2017-09-01;0(0):. 2017-09-01 [PMID: 28864475] (Flow Cytometry, Mouse)	Flow Cytometry	Mouse

Array MAB4729

• C5L2/GPR77 Antibodies
• C5L2/GPR77 Lysate
• C5L2/GPR77 Protein