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C5L2/GPR77 Antibody (468705) [mFluor Violet 500 SE]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
468705
Clonality
Monoclonal
Host
Rat
Conjugate
mFluor Violet 500 SE

Order Details

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C5L2/GPR77 Antibody (468705) [mFluor Violet 500 SE] Summary

Immunogen
Chinese hamster ovary cell line transfected with mouse C5L2
Met1-Val344
Accession # Q8BW93
Specificity
This antibody stains mouse C5L2 transfectants but not irrelevant transfectants.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
C5AR2
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for C5L2/GPR77 Antibody (468705) [mFluor Violet 500 SE]

  • C5a anaphylatoxin chemotactic receptor C5L2
  • C5L2
  • C5L2G-protein coupled receptor 77
  • G protein-coupled receptor 77
  • G protein-coupled receptor C5L2
  • GPF77
  • GPR77

Background

Official Gene Symbol: GPR77 Gen Bank Accession Number: NP_060955 Gene ID: 27202 (human) Gene Map Locus: 19q13.33 (human) C5L2 is 337A.A orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C5AR2