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Human Complement Component C5a DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Human Complement Component C5a DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
C5

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY2037.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Complement Component C5a DuoSet ELISA, 15 Plate

  • C5
  • C5A
  • Complement Component C5a
  • HE

Background

Human complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 alpha-chain. Human C5a has four alpha-helices plus three intrachain disulfide bonds that create a triple loop structure.

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Publications for Complement Component C5a (DY2037)(25)

We have publications tested in 2 confirmed species: Human, Rat.


Filter By Application
All Applications
Filter By Species
Human
(24)
Rat
(1)
All Species
Showing Publications 1 - 10 of 25. Show All 25 Publications.
Publications using DY2037 Applications Species
Park, SY;Eum, DY;Jin, Y;Lee, CY;Shim, JW;Choi, SH;Park, SJ;Heo, K;Choi, YJ; Downregulation of complement factor H attenuates the stemness of MDA?MB?231 breast cancer cells via modulation of the ERK and p38 signaling pathways Oncology letters 2023-12-01 [PMID: 37927420] (Human) Human
Sereti, I;Verburgh, ML;Gifford, J;Lo, A;Boyd, A;Verheij, E;Verhoeven, A;Wit, FWNM;Schim van der Loeff, MF;Giera, M;Kootstra, NA;Reiss, P;Vujkovic-Cvijin, I; Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV Cell reports 2023-10-30 [PMID: 37918403] (Human) Human
Struijf, EM;De la O Becerra, KI;Ruyken, M;de Haas, CJC;van Oosterom, F;Siere, DY;van Keulen, JE;Heesterbeek, DAC;Dolk, E;Heukers, R;Bardoel, BW;Gros, P;Rooijakkers, SHM; Inhibition of cleavage of human complement component C5 and the R885H C5 variant by two distinct high affinity anti-C5 nanobodies The Journal of biological chemistry 2023-06-23 [PMID: 37356719] (Human) Human
DJ Doorduijn, MV Lukassen, MFL van 't Wou, V Franc, M Ruyken, BW Bardoel, AJR Heck, SHM Rooijakker Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5 Elife, 2022-08-10;11(0):. 2022-08-10 [PMID: 35947526] (Human) Human
XR Lim, JWL Tan, GYL Chan, J Hou, L Xie, VHL Goh, J Boon, SSM Lee, CM Teo, SC Tan, KP Leong, BYH Thong, BPL Leung Evaluation of Patients with Vaccine Allergies Prior to mRNA-Based COVID-19 Vaccination Vaccines, 2022-06-27;10(7):. 2022-06-27 [PMID: 35891189] (Human) Human
P Ding, Y Xu, L Li, X Lv, L Li, J Chen, D Zhou, X Wang, Q Wang, W Zhang, T Liao, QH Ji, QY Lei, W Hu Intracellular complement C5a/C5aR1 stabilizes beta-catenin to promote colorectal tumorigenesis Cell Reports, 2022-05-31;39(9):110851. 2022-05-31 [PMID: 35649359] (Human) Human
MAG Sage, KD Cranmer, ML Semeraro, S Ma, EV Galkina, Y Tran, KL Wycoff, JA Sharp A Factor H-Fc fusion protein increases complement-mediated opsonophagocytosis and killing of community associated methicillin-resistant Staphylococcus aureus PLoS ONE, 2022-03-24;17(3):e0265774. 2022-03-24 [PMID: 35324969] (Human) Human
TA Shah, HK Pallera, CL Kaszowski, WT Bass, FA Lattanzio Therapeutic Hypothermia Inhibits the Classical Complement Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy Frontiers in Neuroscience, 2021-02-12;15(0):616734. 2021-02-12 [PMID: 33642979] (Rat) Rat
H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 2021-01-21;11(1):1949. 2021-01-21 [PMID: 33479269] (Human) Human
A Mahajan, L Hasíková, U Hampel, A Grüneboom, X Shan, I Herrmann, F Garreis, F Bock, J Knopf, J Singh, C Schauer, S Mahajan, M Leppkes, F Paulsen, U Schlötzer-, V Krenn, A Jünemann, B Hohberger, G Schett, M Herrmann, LE Muñoz Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation The ocular surface, 2021-01-02;20(0):1-12. 2021-01-02 [PMID: 33401018] (Human) Human
Show All 25 Publications.

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Bioinformatics

Gene Symbol C5