BMP-2 Antibody (253717) [Unconjugated] - Pro form Summary
Immunogen
Mouse myeloma cell line NS0-derived recombinant human BMP‑2 Ala22-Lys281 (Arg245Ser, Arg279Ser) Accession # P12643
Specificity
Detects the pro region of the human BMP-2 precursor in direct ELISAs and Western blots. This antibody does not recognize mature recombinant human BMP‑2.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
BMP2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for BMP-2 Antibody (253717) [Unconjugated] - Pro form
BDA2
BMP2
BMP-2
BMP-2A
BMP2ABone morphogenetic protein 2A
bone morphogenetic protein 2
SSFSC
Background
BMP-2, a member of the transforming growth factor beta (TGF-beta )
superfamily, is synthesized as an inactive precursor protein. The
N-terminal pro region is removed via proteolytic cleavage to liberate a
free 114 amino acid C-terminal fragment that forms a disulfide-linked
active BMP-2 homodimer. BMP-2 modulates growth and differentiation of
many cell types through its interaction with heterodimeric receptors
composed of BMPR-II complexed with BMPR-IA or -IB.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for BMP-2 Antibody (MAB2260). (Showing 1 - 1 of 1 FAQs).
I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.
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