BMP-2 Antibody (110) [Janelia Fluor® 646] Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
This antibody was obtained from a rabbit immunized with purified, recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 (Accession#: NP_001191.1; Gln283-Arg396). |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
BMP2 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for BMP-2 Antibody (110) [Janelia Fluor® 646]
Background
Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
FAQs for BMP-2 Antibody (NBP2-89490JF646). (Showing 1 - 1 of 1 FAQ).
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I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
- Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.
Secondary Antibodies
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