I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?

Name: BMP-2 Antibody (100221) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB3551
Price: 459 USD

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Accepted Answer

Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.

At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, ELISA(Cap)
Clone	100221
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Formulation	Size	Price
Carrier Free MAB3551-SP

Carrier Free MAB3551-500

Immunogen	Chinese hamster ovary cell line CHO-derived recombinant human BMP-2 Gln283-Arg396 Accession # P12643
Specificity	Detects human BMP-2 in ELISAs and Western blots. In Western blots, this antibody shows less than 1% cross-reactivity with recombinant human (rh) BMP‑3, rhBMP-4, rhBMP-5, rhBMP-6, or rhBMP-7.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Mouse
Gene	BMP2
Purity Statement	Protein A or G purified from ascites
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

BMP-2 Antibody (100221) [Unconjugated]

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Publications for BMP-2 Antibody (MAB3551)(14)

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Bioinformatics

Publications using MAB3551	Applications	Species
V Grotheer, N Skrynecki, L Oezel, J Grassmann, J Windolf, CV Suschek Osteogenic differentiation of human mesenchymal stromal cells and fibroblasts differs depending on tissue origin and replicative senescence Scientific Reports, 2021-06-07;11(1):11968. 2021-06-07 [PMID: 34099837] (Western Blot, Human)	Western Blot	Human
MG Kim, CL Kim, YS Kim, JW Jang, GM Lee Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7 Scientific Reports, 2021-02-09;11(1):3378. 2021-02-09 [PMID: 33564092] (Western Blot, Hamster)	Western Blot	Hamster
Zhe A. Cheng, Andres Alba-Perez, Cristina Gonzalez-Garcia, Hannah Donnelly, Virginia Llopis-Hernandez, Vineetha Jayawarna et al. Nanoscale Coatings for Ultralow Dose BMP-2-Driven Regeneration of Critical-Sized Bone Defects Advanced Science 1/23/2019 [PMID: 30693176]
LA Hurst, BJ Dunmore, L Long, A Crosby, R Al-Lamki, J Deighton, M Southwood, X Yang, MZ Nikolic, B Herrera, GJ Inman, JR Bradley, AA Rana, PD Upton, NW Morrell TNF? drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling Nat Commun, 2017-01-13;8(0):14079. 2017-01-13 [PMID: 28084316] (Neutralization, Mouse)	Neutralization	Mouse
Chang C, Yeh S, Lee B, Chen C, Su C, Lin Y, Liu C, Chen H Osteogenic Surface Modification Based on Functionalized Poly-P-Xylylene Coating. PLoS ONE, 2015-09-17;10(9):e0137017. 2015-09-17 [PMID: 26379273] (Bioassay, Human)	Bioassay	Human
Jonathan W. Lowery, Jose M. Amich, Alex Andonian, Vicki Rosen N-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding Cellular and Molecular Life Sciences 8/1/2014 [PMID: 24337809]
A. Sharma, F. Meyer, M. Hyvonen, S. M. Best, R. E. Cameron, N. Rushton Osteoinduction by combining bone morphogenetic protein (BMP)-2 with a bioactive novel nanocomposite Bone & Joint Research 7/1/2012 [PMID: 23610684]
Du Y, Xiao Q, Yip HK Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest. Ophthalmol. Vis. Sci., 2010-02-03;51(7):3764-73. 2010-02-03 [PMID: 20130285] (IHC, Western Blot, Mouse)	IHC, Western Blot	Mouse
Chen YL, Chen PK, Jeng LB, Huang CS, Yang LC, Chung HY, Chang SC Periodontal regeneration using ex vivo autologous stem cells engineered to express the BMP-2 gene: an alternative to alveolaplasty. Gene Ther., 2008-08-14;15(22):1469-77. 2008-08-14 [PMID: 18701911] (Western Blot, Rabbit)	Western Blot	Rabbit
Kane R, Godson C, O'Brien C Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol. Vis., 2008-06-20;14(0):1138-48. 2008-06-20 [PMID: 18587495] (Western Blot, Human)	Western Blot	Human
Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY Targeting of bone morphogenetic protein growth factor complexes to fibrillin. J. Biol. Chem., 2008-03-13;283(20):13874-88. 2008-03-13 [PMID: 18339631] (Western Blot, Human)	Western Blot	Human
Kuns-Hashimoto R, Kuninger D, Nili M, Rotwein P Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin. Am. J. Physiol., Cell Physiol., 2008-02-20;294(4):C994-C1003. 2008-02-20 [PMID: 18287331] (ICC, Immunoprecipitation, Primate - Chlorocebus pygerythrus (Vervet Monkey))	ICC, Immunoprecipitation	Primate - Chlorocebus pygerythrus (Vervet Monkey)
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller ET Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res., 2005-09-15;65(18):8274-85. 2005-09-15 [PMID: 16166304] (Western Blot, Human)	Western Blot	Human
Kayed H, Kleeff J, Keleg S, Guo J, Ketterer K, Berberat P, Giese N, Esposito I, Giese T, Buchler M, Friess H Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer. Int J Cancer, 2004-07-10;110(5):668-76. 2004-07-10 [PMID: 15146555] (Western Blot, Human)	Western Blot	Human
Show All 14 Publications. Collapse Publications.

Gene Symbol	BMP2
Uniprot	P12643()