beta-2 Adrenergic R/ADRB2 Antibody (4C11) Summary
Additional Information |
Recombinant monoclonal antibody expressed in HEK293F cells |
Immunogen |
A synthesized peptide derived from Human beta-2 Adrenergic R/ADRB2 [UniProt P07550] |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
ADRB2 |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Immunohistochemistry 1:50-1:200
|
Packaging, Storage & Formulations
Storage |
Store at -20 to -70C. Avoid freeze-thaw cycles. |
Buffer |
PBS, pH 7.4, 150mM NaCl and 50% glycerol |
Preservative |
0.02% Sodium Azide |
Purity |
Affinity purified |
Alternate Names for beta-2 Adrenergic R/ADRB2 Antibody (4C11)
Background
The beta-2 adrenoceptor (ADRB2) is an Adrenergic Receptor expressed in smooth muscle and metabolic tissues. Activation of this receptor induces a decrease in gastrointestinal motility, bronchodilation, vasodilation in skeletal and cardiac muscle, and glycogenolysis in liver. The beta-2 adrenoceptor is also a major lipolytic receptor in human fat cells and may be involved in obesity. Agonists of ADRB2 are most widely used for the treatment of asthma. In complex with beta-arrestin-1 and c-src, the beta-2 adrenergic receptor activates MAP kinases ERK1(MAPK3) and ERK2 (MAPK1). Expression of the beta-2 adrenoceptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. ESTs have been isolated from breast, liver, liver/spleen, placenta, and uterus libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for beta-2 Adrenergic R/ADRB2 Antibody (NBP3-26521) (0)
Secondary Antibodies
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