Species: Hu, Mu, Rt, Ze
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Monoclonal
Species: Hu, Rt
Applications: WB, ELISA, Flow
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
The beta-2 adrenoceptor (ADRB2) is an Adrenergic Receptor expressed in smooth muscle and metabolic tissues. Activation of this receptor induces a decrease in gastrointestinal motility, bronchodilation, vasodilation in skeletal and cardiac muscle, and glycogenolysis in liver. The beta-2 adrenoceptor is also a major lipolytic receptor in human fat cells and may be involved in obesity. Agonists of ADRB2 are most widely used for the treatment of asthma. In complex with beta-arrestin-1 and c-src, the beta-2 adrenergic receptor activates MAP kinases ERK1(MAPK3) and ERK2 (MAPK1). Expression of the beta-2 adrenoceptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. ESTs have been isolated from breast, liver, liver/spleen, placenta, and uterus libraries.
Bioinformatics
| Entrez |
Mouse
Human
Rat
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
154 |
| Alternate Names |
- ADRBR
- adrenergic, beta-2-, receptor, surface
- B2ARADRB2R
- BAR
- beta-2 adrenergic receptor
- Beta-2 adrenoceptor
- Beta-2 adrenoreceptor
- BETA2AR
- catecholamine receptor
|
![Western Blot beta-2 Adrenergic R/ADRB2 Antibody (2204C) [Unconjugated]](http://images.novusbio.com/fullsize2/beta2_Adrenergic_R_MAB10040_Western_Blot_22819.jpg)
