Reactivity | Hu, Mu, Rt, Po, Pl, RbSpecies Glossary |
Applications | WB, Flow, ICC/IF, IHC, IP, WB, ChIP, CyTOF-ready, KO |
Clone | 70B1413.1 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Alexa Fluor 750 |
Immunogen | This monoclonal antibody was made against a partial protein containing amino acids 1-273 of human ATF6. |
Specificity | This ATF6 antibody detects both the full length and the cleaved/active protein. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | ATF6 |
Purity | Protein G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for ATF6 Antibody (NBP1-40256AF750)Find related products by research area.
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ATF6 - monitoring and regulating protein folding under cellular stress During times of cellular stress overloading of the protein folding machinery leads to the accumulation of incorrectly folded proteins. This triggers the unfolded protein response (UPR) in order to try to reestablish homeostasis or, if this fails, t... Read full blog post. |
ATF6 - a key target in alcohol-induced fatty liver disease? The ATF6 endoplasmic reticulum (ER) stress-regulated transcription factor is constitutively expressed and plays a central role in the mammalian unfolded protein response (UPR). This fundamental pathway is responsible for balancing cellular hom... Read full blog post. |
A Key to Fight Stress: ATF6 The protein ATF6 is a constitutively expressed transcription factor that is a key mediator of the unfolded protein response (UPR) that allows mammalian cells to maintain cellular homeostasis under conditions of environmental and physiological stress. ... Read full blog post. |
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Gene Symbol | ATF6 |