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ERN2 Antibody

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Immunohistochemistry-Paraffin: ERN2 Antibody [NBP3-17487] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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ERN2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: HHELPPVLHTTMLRVHPTLGSGTAETRPPENTQAPAFFLELLSLSREKLWDSELHPEEKTPDSYLGLGPQD
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERN2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for ERN2 Antibody

  • EC 2.7.11
  • endoplasmic reticulum to nucleus signaling 2
  • endoplasmic reticulum to nucleus signalling 2
  • Endoplasmic reticulum-to-nucleus signaling 2
  • ER to nucleus signalling 2
  • hIRE2p
  • inositol-requiring 1 beta
  • Inositol-requiring protein 2
  • IRE1, S. cerevisiae, homolog of
  • Ire1-beta
  • IRE1bIRE1 beta
  • IRE2
  • serine/threonine-protein kinase/endoribonuclease IRE2

Background

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ERN2