Apolipoprotein B/ApoB Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ApoB is a component of LDL and VLDL particles and chylomicans. ApoB100, the full-length ApoB synthesized in the liver, is a 512 kDa secreted palmetoylated glycoprotein that contains 4536 amino acid residues. A truncated ApoB designated ApoB48, containing the N-terminal 48% of ApoB100, is also produced by the intestine as a result of post-transcriptional modification of the ApoB mRNA. Additionally, C-terminal truncated ApoB, varying in length from ApoB25 to ApoB89, exists as a result of mutations in the ApoB gene. Within the region used as the immunogen, the amino acid sequence of the human peptide is 80% and 82% identical to the mouse and canine sequence, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: Co-Immunoprecipitation, ICC, IHC.

Showing Publications 1 - 6 of 6.

Publications using AF3556	Applications	Species
Ye Chen, Xiao Wu, Jing Zhang, Guopin Pan, Xiaoyun Wang, Xiaosun Guo et al. Amino acid starvation‐induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance EMBO reports 3/3/2022 [PMID: 34994492]
Anthony Fringuello, Philip D. Tatman, Tadeusz Wroblewski, John A. Thompson, Xiaoli Yu, Kevin O. Lillehei et al. Cytokine-Laden Extracellular Vesicles Predict Patient Prognosis after Cerebrovascular Accident International Journal of Molecular Sciences 7/22/2021 [PMID: 34360613]
Kijani S, Yrlid U, Heyden M, Levin M, Boren J, Fogelstrand P Filter-Dense Multicolor Microscopy. PLoS ONE, 2015-03-04;10(3):e0119499. 2015-03-04 [PMID: 25739088] (IHC, Mouse)	IHC	Mouse
Yang X, Amar M, Vaisman B, Bocharov A, Vishnyakova T, Freeman L, Kurlander R, Patterson A, Becker L, Remaley A Scavenger receptor-BI is a receptor for lipoprotein(a). J Lipid Res, 2013-06-29;54(9):2450-7. 2013-06-29 [PMID: 23812625] (ICC, Human)	ICC	Human
Baptiste Jammart, Maud Michelet, Eve-Isabelle Pécheur, Romain Parent, Birke Bartosch, Fabien Zoulim et al. Very-Low-Density Lipoprotein (VLDL)-Producing and Hepatitis C Virus-Replicating HepG2 Cells Secrete No More Lipoviroparticles than VLDL-Deficient Huh7.5 Cells Journal of Virology 5/1/2013 [PMID: 23427158]
Nahmias Y, Goldwasser J, Casali M, van Poll D, Wakita T, Chung R, Yarmush M Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. Hepatology, 2008-05-01;47(5):1437-45. 2008-05-01 [PMID: 18393287] (Co-Immunoprecipitation, Human)	Co-Immunoprecipitation	Human

Array AF3556

• Apolipoprotein B/ApoB Antibodies
• Apolipoprotein B/ApoB ELISA Kits
• Apolipoprotein B/ApoB Protein
• Apolipoprotein B/ApoB ELISA