Recombinant Human AMPK beta 1 His Protein

5'-AMP-activated protein kinase subunit beta-1, also known as PRKAB1, inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). Recombinant human PRKAB1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publication using NBP2-23375	Applications	Species
Hsu CC, Zhang X, Wang G et al. Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK Molecular cell 2021-09-16 [PMID: 34547240]

Array NBP2-23375

• AMPK beta 1 Antibodies
• AMPK beta 1 ELISA Kits
• AMPK beta 1 Lysate
• AMPK beta 1 Proteins