Aldolase A Antibody

Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-87488	Applications	Species
Monterisi S, Michl J, Hulikova A et al. Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes eLife 2022-09-15 [PMID: 36107487] (WB, Human)	WB	Human
Rossi M, Altea-Manzano P, Demicco M et al. PHGDH heterogeneity potentiates cancer cell dissemination and metastasis Nature 2022-05-01 [PMID: 35585241] (WB)	WB
Morisaki T, Yashiro M, Kakehashi A, et al. Comparative Proteomics Analysis of Gastric Cancer Stem Cells PLos One. 2014-11-07 [PMID: 25379943] (IF/IHC, WB, Human) Details: Chorein/VPS13A antibody used for IHC- P at 1:500 dilution on gastric cancer tissue specimens - antigen retrieval for 10 minutes at 105C by autoclave in Target Retrieval Solution, endogenous peroxidase blocked with 3%H2O2, On/4C incubation for primary, streptavidin-peroxidase-DAB detection (Figure 3).	IF/IHC, WB	Human
Kjellin H, Johansson H, Hoog A et al. Differentially Expressed Proteins in Malignant and Benign Adrenocortical Tumors. PLoS One 2014-01-01 [PMID: 24498411]
Du S, Guan Z, Hao L et al. Fructose-Bisphosphate Aldolase A Is a Potential Metastasis-Associated Marker of Lung Squamous Cell Carcinoma and Promotes Lung Cell Tumorigenesis and Migration. PLoS One 2014-01-01 [PMID: 24465716]

Array NBP1-87488

• Aldolase A Antibodies
• Aldolase A ELISA Kits
• Aldolase A Lysates
• Aldolase A Proteins