Aldolase A Products

Description

Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.

Bioinformatics

Entrez	100009055 Rabbit 226 Human 24189 Rat
Uniprot	AAH10660 Human AAH10660.1 Human NM_000034 Human NM_184043 Human NP_000025.1 Human NP_001121089 Human NP_908930 Human P04075 Human
Product By Gene ID	226
Alternate Names	ALDA aldolase A, fructose-bisphosphate EC 4.1.2.13 fructose-1,6-bisphosphate triosephosphate-lyase fructose-bisphosphate aldolase A GSD12 Lung cancer antigen NY-LU-1 MGC10942 MGC17716 MGC17767 Muscle-type aldolase

Research Areas for Aldolase A

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Cancer
Cell Cycle and Replication