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alcohol dehydrogenase 7 Antibody (OTI2H10) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, IHC
Clone
OTI2H10
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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alcohol dehydrogenase 7 Antibody (OTI2H10) [Janelia Fluor® 646] Summary

Immunogen
Full length recombinant protein of human alcohol dehydrogenase 7 (NP_000664) produced in HEK293T cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ADH7
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for alcohol dehydrogenase 7 Antibody (OTI2H10) [Janelia Fluor® 646]

  • ADH4
  • ADH-4
  • alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
  • alcohol dehydrogenase class 4 mu/sigma chain
  • Alcohol dehydrogenase class IV mu/sigma chain
  • alcohol dehydrogenase VII
  • alcohol dehydrogenase-7
  • class IV sigma-1 alcohol dehydrogenase
  • class IV sigmasigma alcohol dehydrogenase
  • EC 1.1.1
  • EC 1.1.1.1
  • Gastric alcohol dehydrogenase
  • Retinol dehydrogenase

Background

alcohol dehydrogenase 7 encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADH7