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Aggrecan Antibody

Images

 
Independent Antibodies: Immunohistochemistry-Paraffin: Aggrecan Antibody [NBP2-55539] - Staining of human cerebral cortex, esophagus, rectum and soft tissues using Anti-ACAN antibody NBP2-55539 (A) shows similar ...read more
Immunohistochemistry-Paraffin: Aggrecan Antibody [NBP2-55539] - Staining of human rectum.
Immunohistochemistry-Paraffin: Aggrecan Antibody [NBP2-55539] - Staining of human soft tissues.
Immunohistochemistry-Paraffin: Aggrecan Antibody [NBP2-55539] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: Aggrecan Antibody [NBP2-55539] - Staining of human esophagus.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

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Aggrecan Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTFAPEIGATAFAEVENETGEATRPWGFPTPG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ACAN
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Aggrecan Recombinant Protein Antigen (NBP2-55539PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Aggrecan Antibody

  • ACAN
  • AGC1
  • AGC1SEDK
  • aggrecan core protein
  • Aggrecan
  • Cartilage-specific proteoglycan core protein
  • Chondroitin sulfate proteoglycan 1
  • Chondroitin sulfate proteoglycan core protein 1
  • CSPCP
  • CSPG1
  • CSPG1aggrecan 1
  • CSPGCP
  • large aggregating proteoglycan
  • MSK16
  • MSK16AGCAN
  • SEDK

Background

This aggrecan degradation product usually remains within the tissue still complexed to hyaluronan and link protein. Its release from the cartilage usually signals that there has been extensive catabolism of aggrecan, which allows large complexes containing this metabolite to be released from the tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional Aggrecan Products

Research Areas for Aggrecan Antibody (NBP2-55539)

Find related products by research area.

Blogs on Aggrecan.

Aches & Pains: Aggrecan in Joint Disease and Osteoarthritis
Aggrecan is essential for the normal function of articular cartilage and intervertebral discs. Aggrecan provides the ability for the tissues to withstand compressive loading. This property is dependent on both the high charge density endowed by its nu...  Read full blog post.

mFluor Violet Conjugated Antibodies

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Bioinformatics

Gene Symbol ACAN