Human ADAMTS5 DuoSet ELISA, 5 Plate

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Members of the ADAMTS family contain pro, catalytic, disintegrin-like, cysteine-rich, spacer and a variable number of TS type 1 motifs. In contrast to membrane-anchored ADAMs, ADAMTSs are secreted and are all active proteases. They are essential for aggrecan turnover and procollagen processing, regulation of which is important in many physiological and pathological processes such as angiogenesis and arthritis.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 16. Show All 16 Publications. Collapse Publications.

Publications using DY2198-05	Applications	Species
Sengprasert, P;Waitayangkoon, P;Kamenkit, O;Sawatpanich, A;Chaichana, T;Wongphoom, J;Ngarmukos, S;Taweevisit, M;Lotinun, S;Tumwasorn, S;Tanavalee, A;Reantragoon, R; Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus-conditioned media Scientific reports 2024-08-05 [PMID: 39103466] (Human)		Human
Sun, R;Zhu, J;Sun, K;Gao, L;Zheng, B;Shi, J; Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-?1/NF-?B Axis International journal of medical sciences 2023-10-07 [PMID: 37928874] (Human)		Human
X Wang, D Wang, B Deng, L Yan Syringaresinol attenuates osteoarthritis via regulating the NF-kappaB pathway International immunopharmacology, 2023-03-28;118(0):109982. 2023-03-28 [PMID: 36989902] (Mouse)		Mouse
Z Zhou, L Zhang, Y Liu, C Huang, W Xia, H Zhou, Z Zhou, X Zhou Luteolin Protects Chondrocytes from H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling Oxidative Medicine and Cellular Longevity, 2022-02-01;2022(0):5635797. 2022-02-01 [PMID: 35154568] (Mouse)		Mouse
DF Boyd, EK Allen, AG Randolph, XJ Guo, Y Weng, CJ Sanders, R Bajrachary, NK Lee, CS Guy, P Vogel, W Guan, Y Li, X Liu, T Novak, MM Newhams, TP Fabrizio, N Wohlgemuth, PM Mourani, PALISI Ped, TN Wight, S Schultz-Ch, SA Cormier, K Shaw-Salib, A Pekosz, RE Rothman, KF Chen, Z Yang, RJ Webby, N Zhong, JC Crawford, PG Thomas Exuberant fibroblast activity compromises lung function via ADAMTS4 Nature, 2020-10-28;0(0):. 2020-10-28 [PMID: 33116313] (Human)		Human
J Cassuto, A Folestad, J Göthlin, H Malchau, J Kärrholm Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants Bone Rep, 2020-09-11;13(0):100715. 2020-09-11 [PMID: 32995386] (Human)		Human
Z Zhang, Z Zha, Z Zhao, W Liu, W Li Lentinan Inhibits AGE-Induced Inflammation and the Expression of Matrix-Degrading Enzymes in Human Chondrocytes Drug Des Devel Ther, 2020-07-17;14(0):2819-2829. 2020-07-17 [PMID: 32764881] (Human)		Human
R Liu, H Wu, H Song Knockdown of TRIM8 Attenuates IL-1beta-induced Inflammatory Response in Osteoarthritis Chondrocytes Through the Inactivation of NF-kappaB Pathway Cell Transplant, 2020-01-01;29(0):9636897209436. 2020-01-01 [PMID: 32757662] (Human)		Human
XH Xue, JX Xue, W Hu, FL Shi, Y Yang Nomilin targets the Keap1-Nrf2 signalling and ameliorates the development of osteoarthritis J. Cell. Mol. Med., 2020-06-21;0(0):. 2020-06-21 [PMID: 32564468] (Mouse)		Mouse
J Lee, CY Lee, JH Park, HH Seo, S Shin, BW Song, IK Kim, SW Kim, S Lee, JC Park, S Lim, KC Hwang Differentiation of adipose-derived stem cells into functional chondrocytes by a small molecule that induces Sox9 Exp. Mol. Med., 2020-04-21;0(0):. 2020-04-21 [PMID: 32313200] (Human)		Human
Z Wang, D Ye, J Ye, M Wang, J Liu, H Jiang, Y Xu, J Zhang, J Chen, J Wan ADAMTS-5 Decreases in Coronary Arteries and Plasma from Patients with Coronary Artery Disease Dis. Markers, 2019-12-16;2019(0):6129748. 2019-12-16 [PMID: 31929842] (Human)		Human
D Chen, D Lu, H Liu, E Xue, Y Zhang, P Shang, X Pan Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-alpha-driven inflammation and ER stress EBioMedicine, 2019-11-14;0(0):. 2019-11-14 [PMID: 31735552] (Human)		Human
X Li, J Lin, X Ding, J Xuan, Z Hu, D Wu, X Zhu, Z Feng, W Ni, A Wu The protective effect of sinapic acid in osteoarthritis: In vitro and in vivo studies J. Cell. Mol. Med., 2019-01-03;0(0):. 2019-01-03 [PMID: 30604480] (Human)		Human
X Li, D Wu, Z Hu, J Xuan, X Ding, G Zheng, Z Feng, W Ni, A Wu The Protective Effect of Ligustilide in Osteoarthritis: An in Vitro and in Vivo Study Cell. Physiol. Biochem., 2018-08-17;48(6):2583-2595. 2018-08-17 [PMID: 30121673] (Human)		Human
MH Hwang, HG Son, JW Lee, CM Yoo, JH Shin, HG Nam, HJ Lim, SM Baek, JH Park, JH Kim, H Choi Photobiomodulation of extracellular matrix enzymes in human nucleus pulposus cells as a potential treatment for intervertebral disk degeneration Sci Rep, 2018-08-03;8(1):11654. 2018-08-03 [PMID: 30076336] (Human)		Human
DS Mern, A Tschugg, S Hartmann, C Thomé Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders PLoS ONE, 2017-02-16;12(2):e0172181. 2017-02-16 [PMID: 28207788] (Human)		Human
Show All 16 Publications. Collapse Publications.

Array DY2198-05

• ADAMTS5 Antibodies
• ADAMTS5 ELISA Kit
• ADAMTS5 Proteins
• ADAMTS5 ELISA
• ADAMTS5 Proteins and Enzyme