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Aggrecan Antibody (BC-3) [DyLight 350]

Name: Aggrecan Antibody (BC-3) [DyLight 350]
Brand: Novus Biologicals
SKU: NB600-504UV
Price: 519 USD

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Product Details

Summary

Reactivity	Hu, Mu, Rt, Po, Bv, Ca, Eq, Fe, Gp, Rb, ShSpecies Glossary
Applications	WB, ELISA, ICC/IF, IHC
Clone	BC-3
Clonality	Monoclonal
Host	Mouse
Conjugate	DyLight 350

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 NB600-504AF350

Alexa Fluor 532 NB600-504AF532

Alexa Fluor 594 NB600-504AF594

Alexa Fluor 647 NB600-504AF647-0.1ml

Alexa Fluor 750 NB600-504AF750

Allophycocyanin NB600-504APC

Biotin NB600-504B-100ul

DyLight 405 NB600-504V

DyLight 488 NB600-504G-100ul

DyLight 550 NB600-504R-100ul

DyLight 594 NB600-504DL594

DyLight 650 NB600-504C-100ul

DyLight 680 NB600-504FR

DyLight 755 NB600-504IR

FITC NB600-504F

HRP NB600-504H-100ul

Janelia Fluor 549 NB600-504JF549

Janelia Fluor 646 NB600-504JF646

PE NB600-504PE

PerCP NB600-504PCP

Unconjugated NB600-504-0.1mg

mFluor Violet 450 SE NB600-504MFV450

mFluor Violet 500 SE NB600-504MFV500

mFluor Violet 610 SE NB600-504MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Standard Formulation NB600-504-0.1mg

BSA Free NB600-504-0.1mg

BSA Free NB600-504-0.025mg

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Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	NB600-504AF350
Alexa Fluor 532	NB600-504AF532
Alexa Fluor 594	NB600-504AF594
Alexa Fluor 647	NB600-504AF647-0.1ml
Alexa Fluor 750	NB600-504AF750
Allophycocyanin	NB600-504APC
Biotin	NB600-504B-100ul
DyLight 405	NB600-504V
DyLight 488	NB600-504G-100ul
DyLight 550	NB600-504R-100ul
DyLight 594	NB600-504DL594
DyLight 650	NB600-504C-100ul
DyLight 680	NB600-504FR
DyLight 755	NB600-504IR
FITC	NB600-504F
HRP	NB600-504H-100ul
Janelia Fluor 549	NB600-504JF549
Janelia Fluor 646	NB600-504JF646
PE	NB600-504PE
PerCP	NB600-504PCP
Unconjugated	NB600-504-0.1mg
mFluor Violet 450 SE	NB600-504MFV450
mFluor Violet 500 SE	NB600-504MFV500
mFluor Violet 610 SE	NB600-504MFV610

Aggrecan Antibody (BC-3) [DyLight 350] Summary

Immunogen	ARGSV... synthetic peptide conjugate.
Localization	Secreted
Marker	Chondrocyte Marker
Specificity	Recognizes the aggrecanase (ADAMTS-1, -4 & -5)-generated N-terminal neoepitope ARG after cleavage between amino acids EGE and ARG within the interglobular domain of aggrecanase-catabolised aggrecan.
Isotype	IgG1 Kappa
Clonality	Monoclonal
Host	Mouse
Gene	ACAN
Purity	Protein A or G purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	ELISA Immunocytochemistry/ Immunofluorescence Immunohistochemistry Immunohistochemistry-Frozen Immunohistochemistry-Paraffin Western Blot
Application Notes	Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Cross-reacts with Human, Cow, Cat, Dog, Guinea pig, Horse, Pig, Rabbit, Rat and Sheep. Mouse reactivity reported in scientific literature (PMID: 27185069). Not yet tested in other species.

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Aggrecan Antibody (BC-3) [DyLight 350]

ACAN
AGC1
AGC1SEDK
aggrecan core protein
Aggrecan
Cartilage-specific proteoglycan core protein
Chondroitin sulfate proteoglycan 1
Chondroitin sulfate proteoglycan core protein 1
CSPCP
CSPG1
CSPG1aggrecan 1
CSPGCP
large aggregating proteoglycan
MSK16
MSK16AGCAN
SEDK

Background

This aggrecan degradation product usually remains within the tissue still complexed to hyaluronan and link protein. Its release from the cartilage usually signals that there has been extensive catabolism of aggrecan, which allows large complexes containing this metabolite to be released from the tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Aggrecan Antibody
(BC-3) [DyLight 350]

NB600-504UV

Species: Hu, Mu, Rt, Po, Bv, Ca, Eq, Fe, Gp, Rb, Sh

Applications: WB, ELISA, ICC/IF, IHC

Publications for Aggrecan Antibody (NB600-504UV) (0)

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

Isotype Controls

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Research Areas for Aggrecan Antibody (NB600-504UV)

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Blogs on Aggrecan.

Check out the latest blog posts on Aggrecan.

Aches & Pains: Aggrecan in Joint Disease and Osteoarthritis
Aggrecan is essential for the normal function of articular cartilage and intervertebral discs. Aggrecan provides the ability for the tissues to withstand compressive loading. This property is dependent on both the high charge density endowed by its nu... Read full blog post.

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Bioinformatics

Gene Symbol

ACAN

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Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Help Finding Antibodies Protocols

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Aggrecan Antibody (BC-3) [DyLight 350]

Species Glossary

Images

Product Details

Order Details

Aggrecan Antibody (BC-3) [DyLight 350] Summary

Applications/Dilutions

Reactivity Notes

Packaging, Storage & Formulations

Notes

Alternate Names for Aggrecan Antibody (BC-3) [DyLight 350]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for Aggrecan Antibody (NB600-504UV) (0)

Reviews for Aggrecan Antibody (NB600-504UV) (0)

Product General Protocols

Video Protocols

FAQs for Aggrecan Antibody (NB600-504UV) (0)

Secondary Antibodies

Isotype Controls

Additional Aggrecan Products

Research Areas for Aggrecan Antibody (NB600-504UV)

Blogs on Aggrecan.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics