ACSL1 Antibody [FITC]

ACSL1 (long-chain-fatty-acid--CoA ligase 1), belongs to ATP-dependent AMP-binding enzyme family and is one of the 5 isoforms (ACSL - 1, -3, -4, -5 and -6) of long chain acyl CoA synthetases (ACSLs), the enzymes which plays a crucial role in regulating fatty acid metabolism by converting free fatty acids (FFAs) into fatty acyl CoA derivatives via a process called fatty acid activation, a modification required for any FFA to undergo further metabolism. ACSL1 is a single-pass type III membrane protein localized in mitochondrion outer membrane and membranes of peroxisomes, microsomes, ER of energy-metabolizing tissues such as fat, liver, and skeletal muscles. ACSL1 is a central enzyme in the intermediary metabolism due to its fundamental role in activation of long-chain fatty acids through the incorporation of CoA. These bioactive fatty acid metabolites are involved in many cellular biochemical processes, including protein transport, enzyme activation, and transcriptional control. Additionally, fatty acyl-CoAs are used as substrates in fatty acid beta-oxidation and the phospholipid biosynthesis pathways.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NB110-99585F

• ACSL1 Antibodies
• ACSL1 Proteins