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YME1L1 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: YME1L1 Antibody [NBP2-49499] - Staining of human cell line U-2 OS shows localization to nuclear bodies & mitochondria.
Immunohistochemistry-Paraffin: YME1L1 Antibody [NBP2-49499] - Staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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YME1L1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: AVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVS
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
YME1L1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
YME1L1 Recombinant Protein Antigen (NBP2-49499PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for YME1L1 Antibody

  • ATP-dependent metalloprotease FtsH1 homolog
  • ATP-dependent metalloprotease FtsH1
  • ATP-dependent metalloprotease YME1L1
  • EC 3.4.24
  • EC 3.4.24.-
  • FTSH
  • FTSH1
  • MEG4
  • Meg-4
  • PAMPATP-dependent zinc metalloprotease YME1L1
  • Presenilin-associated metalloprotease
  • YME1 (S.cerevisiae)-like 1
  • YME1-like 1 (S. cerevisiae)
  • YME1-like protein 1
  • YME1Lmeg-4

Background

The protein encoded by the YME1L1 gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol YME1L1