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WNK4 Antibody [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IP, MS, ICC/IF (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

Order Details

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WNK4 Antibody [mFluor Violet 610 SE] Summary

Immunogen
A synthetic peptide made to a region of the human WNK4 protein between residues 200-300. [UniProt# Q96J92]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
WNK4
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Electron Microscopy
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Use in Rat reported in scientific literature (PMID:34448462).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for WNK4 Antibody [mFluor Violet 610 SE]

  • EC 2.7.11
  • EC 2.7.11.1
  • PHA2B
  • PRKWNK4protein kinase, lysine deficient 4
  • Protein kinase lysine-deficient 4
  • Protein kinase with no lysine 4
  • serine/threonine-protein kinase WNK4
  • WNK lysine deficient protein kinase 4

Background

WNK lysine deficient protein kinase 4 (WNK4) is a cytoplasmic serine-threonine kinase expressed in the distal nephron which likely plays an important role in hypertension. The role of WNK4 in kidney physiology is to act as a molecular switch between NaCl reabsorption (volume retention) and K+ secretion (waste release).

WNK4 mutations have been associated with an autosomal dominant disease called pseudohypoaldosteronism type II.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional WNK4 Products

Array NB600-284MFV610

Research Areas for WNK4 Antibody (NB600-284MFV610)

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Bioinformatics

Gene Symbol WNK4